736140-69-5

Basic information

• Product Name: (2E)-3-(4-methylphenyl)-1-pyrrol-1-yl-2-propen-1-one
• Synonyms: (2E)-3-(4-methylphenyl)-1-pyrrol-1-yl-2-propen-1-one
• CAS NO: 736140-69-5
• Molecular Weight: 211.263
• Mol File: 736140-69-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2E)-3-(4-methylphenyl)-1-pyrrol-1-yl-2-propen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-3-(4-methylphenyl)-1-pyrrol-1-yl-2-propen-1-one(736140-69-5)
• EPA Substance Registry System: (2E)-3-(4-methylphenyl)-1-pyrrol-1-yl-2-propen-1-one(736140-69-5)

Safety Data

• Hazardous Substances Data: 736140-69-5(Hazardous Substances Data)

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 627546-31-0 1-(1H-pyrrol-1-yl)-2-(triphenylphosphoranylidene)ethanone 
• 54582-33-1 1,1'-carbonyldiimidazole 

Downstream Products

• 1608108-59-3 ((1S,2S,3R)-4-methylene-2-(p-tolyl)-3-((trimethylsilyl)ethynyl)cyclopentyl)(1H-pyrrol-1-yl)methanone 
• 532-65-0 (+)-(S)-ar-turmerone 
• 151765-65-0 (S)-3-(4-methylphenyl)butanal 
• 1461-10-5 (S)-3-(4-methylphenyl)-1-butanol 
• 1448857-55-3 (S)-1-(1H-pyrrol-1-yl)-3-(p-tolyl)butan-1-one 

Relevant articles and documents

Sequential Wittig olefination-catalytic asymmetric epoxidation with reuse of waste Ph3P(O): Application of α,β-unsaturated N-Acyl pyrroles as ester surrogates

Waste not, want not: Efficient one-pot access to optically active epoxides with 96 to 99.5% ee from a variety of aldehydes is described. In a sequential process, the Ph3P(O) by-product of a Wittig reaction acts as a modulator for the samarium catalyst in the asymmetric epoxidation of the conjugated N-acyl pyrrole Wittig product (see scheme). The N-acyl pyrrole functionality is key to the high reactivity and selectivity observed. R = alkyl, aryl, vinyl.