73839-24-4

Basic information

• Product Name: 6-(O-Phosphorylcholine)hydroxyhexanoic Acid
• Synonyms: 2-[[[(5-Carboxypentyl)oxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-ethanaminium Inner Sal;6-(O-Phosphorylcholine)hydroxyhexanoic Acid;2-[[[(5-Carboxypentyl)oxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-ethanaminium Inner Salt;6-(O-phosphocholine)oxyhexanoic acid
• CAS NO: 73839-24-4
• Molecular Formula: C₁₁H₂₄NO₆P
• Molecular Weight: 0
• Product Categories: Phospholipids - 13C & 2H;Phosphorylating and Phosphitylating Agents
• Mol File: 73839-24-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• Solubility: Methanol (Slightly), Water (Slightly)
• CAS DataBase Reference: 6-(O-Phosphorylcholine)hydroxyhexanoic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(O-Phosphorylcholine)hydroxyhexanoic Acid(73839-24-4)
• EPA Substance Registry System: 6-(O-Phosphorylcholine)hydroxyhexanoic Acid(73839-24-4)

Safety Data

• Hazardous Substances Data: 73839-24-4(Hazardous Substances Data)

Usage

Description

6-(O-Phosphorylcholine)hydroxyhexanoic Acid, also known as a phosphorylcholine ester, is a compound characterized by a phosphocholine linked to 6-hydroxyhexanoic acid via a phosphodiester linkage. It is a novel derivative with potential applications in various fields, particularly in immunological studies.

Uses

Used in Immunological Studies:
6-(O-Phosphorylcholine)hydroxyhexanoic Acid is used as a novel phosphorylcholine ester for probes in immunological studies. Its unique structure allows for specific interactions with biological systems, making it a valuable tool for investigating immune responses and related phenomena.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 6-(O-Phosphorylcholine)hydroxyhexanoic Acid is used as a key component in the development of new drugs targeting various diseases. Its ability to interact with biopolymers and macromolecules makes it a promising candidate for drug design and formulation.
Used in Drug Delivery Systems:
6-(O-Phosphorylcholine)hydroxyhexanoic Acid is also utilized in the development of drug delivery systems, where it can enhance the targeting and bioavailability of therapeutic agents. Its unique properties may contribute to the design of more effective and targeted drug delivery platforms.

InChI:InChI=1/C11H24NO6P/c1-12(2,3)8-10-18-19(15,16)17-9-6-4-5-7-11(13)14/h4-10H2,1-3H3,(H-,13,14,15,16)

Upstream product

• 73839-23-3 tert-butyl 6-(O-phosphorylcholine)hydroxyhexanoate 
• 73839-25-5 tert-butyl 6-(O-(2-bromoethyl)phosphoryl)hydroxyhexanoate 
• 75-50-3 trimethylamine 
• 134046-84-7 Ethyl 6-(O-phosphorylcholine)hydroxyhexanoate 
• 4224-70-8 6-bromohexanoic acid 
• 25542-62-5 6-bromo-hexanoic acid ethyl ester 
• 65868-63-5 tert-butyl 6-bromohexanoate 
• 73839-20-0 tert-butyl 6-hydroxyhexanoate 
• 4826-71-5 phosphorylcholine chloride, calcium salt 

Downstream Products

• 73785-43-0 p-nitrophenyl 6-(O-phosphorylcholine)hydroxyhexanoate 

Relevant articles and documents

SYNTHESIS OF PHOSPHOCHOLINE ESTER DERIVATIVES AND CONJUGATES THEREOF

Aspects of the present invention include methods of synthesizing phosphocholine analogues and the phosphocholine conjugates formed therefrom and their use in preventing infections caused by microorganisms.

Synthesis of Two Novel Phosphorylcholine Esters for Probes in Immunological Studies

For use in immunological studies on phosphorylcholine (PC)-binding immunoglobulins, two PC esters were synthesized.Ester 5, obtained in 65percent overall yield, contained a covalently bound mercury atom at a specific site as required in an X-ray diffracti