73986-27-3Relevant articles and documents
Effects of substitution on the pyrrole N atom in derivatives of tetrahydronaltrindole, tetrahydrooxymorphindole, and a related 4,5-epoxyphenylpyrrolomorphinan
Srivastava, Sanjay K.,Shefali,Miller, Carl N.,Aceto, Mario D.,Traynor, John R.,Lewis, John W.,Husbands, Stephen M.
, p. 6645 - 6648 (2004)
The effect of substitution of the pyrrolo- and indolo-N atoms in tetrahydronaltrindole (TNTI), tetrahydrooxymorphindole (TOMI), and 17-cyclopropylmethyl-3,14-dihydroxy-4,5-epoxy-4′-phenyl-6,7:2′, 3′-pyrrolomorphinan (4) is reported. In opioid functional a
4'-Arylpyrrolomorphinans: effect of a pyrrolo-N-benzyl substituent in enhancing delta-opioid antagonist activity.
Srivastava, Sanjay K,Husbands, Stephen M,Aceto, Mario D,Miller, Carl N,Traynor, John R,Lewis, John W
, p. 537 - 540 (2002)
A new method for the preparation of N-benzylpyrrolomorphinans has been developed. Thus Michael reaction of the benzylimines of oxycodones and oxymorphones with nitrostyrenes gave a series of 4'-aryl-N-benzylpyrrolomorphinans. These were selective delta an
Stereospecific synthesis of the 6α- and 6β-amino derivatives of naltrexone and oxymorphone
Sayre,Portoghese
, p. 3366 - 3368 (2007/10/02)
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