741683-19-2

Basic information

• Product Name: 3-Chloro-2-fluoroisonicotinic acid
• Synonyms: 3-Chloro-2-fluoropyridine-4-carboxylic acid;3-Chloro-2-fluoro-4-pyridinecarboxylic acid
• CAS NO: 741683-19-2
• Molecular Formula: C₆H₃ClFNO₂
• Molecular Weight: 175.55
• Mol File: 741683-19-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 154 °C (decomp)(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
• Boiling Point: 404.1°C at 760 mmHg
• Flash Point: 198.2°C
• Appearance: /
• Density: 1.576g/cm³
• Vapor Pressure: 2.95E-07mmHg at 25°C
• Refractive Index: 1.563
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.50±0.28(Predicted)
• CAS DataBase Reference: 3-Chloro-2-fluoroisonicotinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-2-fluoroisonicotinic acid(741683-19-2)
• EPA Substance Registry System: 3-Chloro-2-fluoroisonicotinic acid(741683-19-2)

Safety Data

• Hazardous Substances Data: 741683-19-2(Hazardous Substances Data)

Usage

General Description

3-Chloro-2-fluoroisonicotinic acid is a synthetic, halogenated derivative of isonicotinic acid, an organic compound often used in chemistry for its diverse pharmacological properties. Its molecular formula is C6H3ClFNO2 and it is primarily used as an intermediate or base material in the manufacturing of more complex chemical substances, including pharmaceutical drugs and biologically active compounds. It is highly specialized and mainly utilized in research and industrial environments. The properties of 3-Chloro-2-fluoroisonicotinic acid, such as its reactivity and physical stability, make it a key ingredient in various chemical reactions.

InChI:InChI=1/C6H3ClFNO2/c7-4-3(6(10)11)1-2-9-5(4)8/h1-2H,(H,10,11)

Upstream product

• 1480-64-4 3-chloro-2-fluoropyridine 
• 124-38-9 carbon dioxide 
• 2402-77-9 2,3-dichloro-pyridine 

Downstream Products

• 741683-20-5 1'-benzylspiro[4-chloro-5-fluoro-6-azaisobenzofuran-1(3H)-4-piperidin]-3-one 

Relevant articles and documents

CYCLOALKANOPYRIDINE DERIVATIVE

Provided are cycloalkanopyridine derivatives of formula [I]: [wherein the symbols are the same as those stated in the description]. The compounds act as a nociceptin receptor antagonist, and are useful as medicines for diseases associated with a nociceptin receptor, for example, as a reliever against tolerance to a narcotic analgesic; a reliever against dependence on or addiction to a narcotic analgesic; an analgesic enhancer; an antiobesitic or appetite suppressor; a treating or prophylactic agent for cognitive impairment and dementia/amnesia; an agent for treating developmental cognitive abnormality; a remedy for schizophrenia; an agent for treating neurodegenerative diseases; an anti-depressant or treating agent for affective disorder; a treating or prophylactic agent for diabetes insipidus; a treating or prophylactic agent for polyuria; or a remedy for hypotension.