74476-71-4

Basic information

• Product Name: ethyl 2-(2-chlorobenzoyl)-3-oxobutanoate
• Synonyms: ethyl 2-(2-chlorobenzoyl)-3-oxobutanoate
• CAS NO: 74476-71-4
• Molecular Weight: 268.697
• Mol File: 74476-71-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 2-(2-chlorobenzoyl)-3-oxobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(2-chlorobenzoyl)-3-oxobutanoate(74476-71-4)
• EPA Substance Registry System: ethyl 2-(2-chlorobenzoyl)-3-oxobutanoate(74476-71-4)

Safety Data

• Hazardous Substances Data: 74476-71-4(Hazardous Substances Data)

Upstream product

• 118-91-2 ortho-chlorobenzoic acid 
• 141-97-9 ethyl acetoacetate 
• 609-65-4 o-chlorobenzoyl chloride 

Downstream Products

• 1034378-79-4 ethyl 3-(o-chlorophenyl)-5-methyl-1H-pyrazole-4-carboxylate 
• 91063-35-3 5-(2-chloro-phenyl)-3-methyl-isoxazole-4-carboxylic acid amide 
• 19112-35-7 ethyl (2-chlorobenzoyl)acetate 
• 91182-88-6 5-(2-chlorophenyl)-3-methylisoxazole-4-carboxylic acid 

Relevant articles and documents

Amide compound and application thereof as TGR5 agonist

Belonging to the technical field of medicine, the invention in particular relates to an amide TGR5 agonist compound shown as formula (I), its pharmaceutically acceptable salts, esters, stereoisomers, solvent compounds or prodrugs, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, X, Y, Z, and ring A are defined as the specification. The invention also relates to a preparation method of the compounds, pharmaceutical preparations, pharmaceutical compositions, and application of the compounds in preparation of drugs for treatment and/or prevention of TGR5 activity regulation related diseases. (formula (I)).