74526-84-4

Basic information

• Product Name: 5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene
• Synonyms: 5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene
• CAS NO: 74526-84-4
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.25424
• Mol File: 74526-84-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 43-44 °C
• Boiling Point: 331.9°Cat760mmHg
• Flash Point: 139.6°C
• Appearance: /
• Density: 1.043g/cm³
• Vapor Pressure: 0.000292mmHg at 25°C
• Refractive Index: 1.524
• CAS DataBase Reference: 5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene(74526-84-4)
• EPA Substance Registry System: 5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene(74526-84-4)

Safety Data

• Hazardous Substances Data: 74526-84-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H16O2/c1-13-11-7-8-12(14-2)10-6-4-3-5-9(10)11/h7-8H,3-6H2,1-2H3

Upstream product

• 10075-62-4 1,4-dimethoxynaphthalene 
• 55077-80-0 1,4-Dimethoxy-5,6-dihydronaphthalene 
• 13623-10-4 5,6,7,8-tetrahydronaphthalene-1,4-diol 
• 77-78-1 dimethyl sulfate 
• 37464-90-7 5,8-dimethoxy-2-tetralone 
• 141-52-6 sodium ethanolate 
• 7803-57-8 hydrazine hydrate 
• 529-35-1 5,6,7,8-Tetrahydronaphthalen-1-ol 
• 22658-04-4 4-amino-5,6,7,8-tetrahydronaphthalen-1-ol 
• 7474-90-0 5,6,7,8-tetrahydro-1,4-naphthoquinone 
• 55077-79-7 5,8-dimethoxy-1,4-dihydronaphthalene 
• 130-15-4 [1,4]naphthoquinone 
• 1015-55-0 5,8-dimethoxytetralone 

Downstream Products

• 82891-37-0 6-(2-methoxybenzoyl)-5,8-dimethoxytetralin 
• 84390-71-6 methyl 7-(2-chlorobenzoyl)-1,2,3,4-tetrahydro-5,8-dimethoxy-6-naphthylacetate 
• 84390-74-9 methyl 7-(2-chloro-3-methoxybenzoyl)-1,2,3,4-tetrahydro-5,8-dimethoxy-6-naphthylacetate 
• 87923-75-9 5,8-dimethoxy-6-(phenylthio)tetralin 
• 87923-64-6 6-Benzenesulfonyl-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalene 
• 82891-38-1 6-(2-hydroxybenzoyl)-5,8-dihydroxytetralin 
• 13623-10-4 5,6,7,8-tetrahydronaphthalene-1,4-diol 

Relevant articles and documents

Intramolecular Benzyne–Phenolate [4+2] Cycloadditions

An intramolecular benzyne–phenolate [4+2] cycloaddition is reported. Benzyne precursors, having vicinal halogen-sulfonate functionalities, linked with a phenol(ate) by various tether groups undergo efficient intramolecular [4+2] cycloaddition by treatment with either Ph3MgLi or nBuLi for halogen–metal exchange to form various benzobarrelenes.

Synthesis and Demethylation of New 5,6,7,8-Tetrahydro-4,9-dimethoxy-1H-benzindole

The title compound 17 was prepared in good yield starting from 5,6,7,8-tetrahydro-1-naphthol (9) by an advantageous synthesis route consisting of eight steps, as indicated in Scheme 2.Demethylation by reflux heating with anhydrous aluminium chloride in dry benzene furnished 4,9-dihydroxy- and 4,9-dioxo-5,6,7,8-tetrahydro-1H-benzindoles (compounds 18 an 19, respectively).All new products were identified on the basis of spectral and analytical data.