7474-90-0

Basic information

• Product Name: 5,6,7,8-Tetrahydro-1,4-naphthalenedione
• Synonyms: 5,6,7,8-Tetrahydro-1,4-naphthalenedione
• CAS NO: 7474-90-0
• Molecular Formula: C₁₀H₁₀O₂
• Molecular Weight: 162.1852
• Mol File: 7474-90-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 278.2°Cat760mmHg
• Flash Point: 103.4°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 0.00433mmHg at 25°C
• Refractive Index: 1.553
• CAS DataBase Reference: 5,6,7,8-Tetrahydro-1,4-naphthalenedione(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6,7,8-Tetrahydro-1,4-naphthalenedione(7474-90-0)
• EPA Substance Registry System: 5,6,7,8-Tetrahydro-1,4-naphthalenedione(7474-90-0)

Safety Data

• Hazardous Substances Data: 7474-90-0(Hazardous Substances Data)

Usage

General Description

5,6,7,8-Tetrahydro-1,4-naphthalenedione, also known as tetralone, is a chemical compound with a molecular formula C10H10O2. It is a yellow solid that is soluble in organic solvents and has a distinctive odor. Tetralone is commonly used as a precursor in the synthesis of various pharmaceuticals, agrochemicals, and dyes, and it also has potential applications in the production of fragrances and flavors. It is an important intermediate in the manufacture of vitamin E and its derivatives, and it can also be used as a starting material for the synthesis of indole alkaloids. In addition, tetralone has been investigated for its potential antioxidant and anti-inflammatory properties, making it a subject of interest in the development of new therapeutic agents.

InChI:InChI=1/C10H10O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h5-6H,1-4H2

Upstream product

• 861331-69-3 5,6,7,8-tetrahydro-naphthalene-1,4-diyldiamine 
• 13623-10-4 5,6,7,8-tetrahydronaphthalene-1,4-diol 
• 22658-04-4 4-amino-5,6,7,8-tetrahydronaphthalen-1-ol 
• 160035-38-1 6-(tert-butylperoxy)bicyclo[4.4.0]deca-1,4-dien-3-one 
• 7647-01-0 hydrogenchloride 
• 64-17-5 ethanol 
• 7705-08-0 iron(III) chloride 
• 64-19-7 acetic acid 
• 1125-78-6 5,6,7,8-Tetrahydro-2-naphthol 
• 529-35-1 5,6,7,8-Tetrahydronaphthalen-1-ol 
• 130-15-4 [1,4]naphthoquinone 
• 119-64-2 tetralin 

Downstream Products

• 443-76-5 2-aziridin-1-yl-5,6,7,8-tetrahydro-[1,4]naphthoquinone 
• 13623-10-4 5,6,7,8-tetrahydronaphthalene-1,4-diol 
• 7475-34-5 5,6,8-triacetoxy-1,2,3,4-tetrahydro-naphthalene 
• 106381-17-3 2-[bis-(2-chloro-ethyl)-amino]-5,6,7,8-tetrahydro-[1,4]naphthoquinone 
• 58976-97-9 6,11-dihydroxy-7,8,9,10-tetrahydro-5,12-naphthacene-quinone 
• 74526-84-4 1,2,3,4-tetrahydro-5,8-dimethoxynaphthalene 
• 91715-49-0 6-hydroxy-1,2,3,4-tetrahydronaphthalene-5,8-dione 

Relevant articles and documents

Organophotocatalytic Aerobic Oxygenation of Phenols in a Visible-Light Continuous-Flow Photoreactor

A mild photocatalytic phenol oxygenation enabled by a continuous-flow photoreactor using visible light and pressurized air is described herein. Products for wide-ranging applications, including the synthesis of vitamins, were obtained in high yields by precisely controlling principal process parameters. The reactor design permits low organophotocatalyst loadings to generate singlet oxygen. It is anticipated that the efficient aerobic phenol oxygenation to benzoquinones and p-quinols contributes to sustainable synthesis.

Direct access to 1,4-dihydroxyanthraquinones: The Hauser annulation reexamined with p-quinones

(Chemical Equation Presented) 3-Phenylsulfanylphthalides (e.g. 8a) readily react with p-benzoquinones in the presence of LiOtBu in THF to furnish 1,4-dihydroxyanthraquinones in good yields and one-pot operations.

Quinone-amine reactions, XIII: Syntheses of quinoxalinones and naphthoquinoxalinone for colour comparison with benzoquinoxalinones

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