74585-36-7

Basic information

• Product Name: Acetamide, N-(2-chlorophenyl)-N-(phenylmethyl)-
• CAS NO: 74585-36-7
• Molecular Formula: C15H14ClNO
• Molecular Weight: 259.735
• Mol File: 74585-36-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetamide, N-(2-chlorophenyl)-N-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-(2-chlorophenyl)-N-(phenylmethyl)-(74585-36-7)
• EPA Substance Registry System: Acetamide, N-(2-chlorophenyl)-N-(phenylmethyl)-(74585-36-7)

Safety Data

• Hazardous Substances Data: 74585-36-7(Hazardous Substances Data)

Upstream product

• 533-17-5 N-(2-chlorophenyl)acetamide 
• 95-51-2 o-chloroaniline 

Downstream Products

• 7135-32-2 1-benzylindolin-2-one 
• 343221-51-2 N-acetyl-N-benzyl-m-phenylenediamine 

Relevant articles and documents

Photoinduced Cyclizations of Mono- and Dianions of N-Acyl-o-chloroanilines and N-Acyl-o-chlorobenzylamines as General Methods for the Synthesis of Oxindoles and 1,4-Dihydro-3(2H)-isoquinolinones

Formation of the monoanions of a series of N-acyl-N-alkyl-o-chloroanilines by means of LDA in THF followed by irradiation with near-UV light affords 1,3-dialkyloxindoles in good yields.Similar photoinduced cyclizations of dianions derived from N-acyl-o-chloroanilines leads to 3-alkyloxindoles.Photocyclizations of mono- and dianion prepared from α,β-unsaturated o-haloanilides proceed to form 3-alkylideneoxindoles.Carbanions derived from N-acyl-o-chlorobenzylamines also undergo photoassisted ring closure to afford 1,4-dihydro-3(2H)-isoquinolinones.The influence of near-UV light and the effect of inhibitors implicate a radical-chain mechanism as the major reaction pathway in this convenient new method for oxindole and isoquinolinone synthesis.