7461-40-7

Basic information

• Product Name: N-(4-bromophenyl)-4-chlorobenzamide
• Synonyms: N-(4-bromophenyl)-4-chlorobenzamide
• CAS NO: 7461-40-7
• Molecular Formula: C₁₃H₉BrClNO
• Molecular Weight: 310.57366
• Mol File: 7461-40-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 332°Cat760mmHg
• Flash Point: 154.6°C
• Appearance: /
• Density: 1.58g/cm³
• Vapor Pressure: 0.00015mmHg at 25°C
• Refractive Index: 1.67
• CAS DataBase Reference: N-(4-bromophenyl)-4-chlorobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-bromophenyl)-4-chlorobenzamide(7461-40-7)
• EPA Substance Registry System: N-(4-bromophenyl)-4-chlorobenzamide(7461-40-7)

Safety Data

• Hazardous Substances Data: 7461-40-7(Hazardous Substances Data)

Usage

General Description

N-(4-bromophenyl)-4-chlorobenzamide is a chemical compound that belongs to the class of benzamides. N-(4-bromophenyl)-4-chlorobenzamide is formed by the substitution of the hydrogen atom of the amide group of benzamide with a 4-bromophenyl group and a 4-chlorophenyl group. It is often used as a building block in the synthesis of various pharmaceuticals and agrochemicals. N-(4-bromophenyl)-4-chlorobenzamide is also known for its potential biological activities, such as antibacterial and antifungal properties. Additionally, it is used as a reagent in organic synthesis and in the preparation of various derivatives for research and drug discovery purposes.

InChI:InChI=1/C13H9BrClNO/c14-10-3-7-12(8-4-10)16-13(17)9-1-5-11(15)6-2-9/h1-8H,(H,16,17)

Upstream product

• 6833-15-4 4-chlorobenzanilide 
• 122-01-0 4-chloro-benzoyl chloride 
• 62-53-3 aniline 

Downstream Products

• 21011-43-8 4-Chlor-thiobenz-(4-brom-anilid) 
• 16124-43-9 4'-Brom-4-chlor-N-nitrosobenzanilid 

Relevant articles and documents

Combining Eosin y with Selectfluor: A Regioselective Brominating System for Para-Bromination of Aniline Derivatives

A mild, metal-free, and absolutely para-selective bromination of aniline derivatives has been developed in excellent yields, wherein the organic dye Eosin Y is employed as the bromine source in company with Selectfluor. Neither air nor moisture sensitive, this facile reaction proceeds smoothly at room temperature and completes within a short time. Mechanistic studies indicate a radical pathway; therefore, the existence of an in situ generated brominating reagent, "Selectbrom", is postulated, which may reasonably account for the unique regioselectivity for the para-bromination of N-acyl- as well as N-sulfonylanilines.