74672-02-9

Basic information

• Product Name: 3,5-dichloro-2-nitrophenol
• Synonyms: 3,5-dichloro-2-nitrophenol
• CAS NO: 74672-02-9
• Molecular Weight: 208.001
• Mol File: 74672-02-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3,5-dichloro-2-nitrophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dichloro-2-nitrophenol(74672-02-9)
• EPA Substance Registry System: 3,5-dichloro-2-nitrophenol(74672-02-9)

Safety Data

• Hazardous Substances Data: 74672-02-9(Hazardous Substances Data)

Upstream product

• 591-35-5 3,5-dichlorophenol 
• 7664-93-9 sulfuric acid 

Downstream Products

• 56962-03-9 2-amino-3,5-dichlorophenol 
• 74672-01-8 3,5-dichloro-2-nitroanisole 
• 74672-00-7 5-Chlor-3-hydroxy-2-nitrodiphenylamin 
• 100948-83-2 3,5-dichloro-4-nitroanisole 
• 93839-14-6 2,4-dichloro-6-methoxyaniline 
• 158966-63-3 1-(2,4-Dichloro-6-methoxy-phenyl)-1H-pyrrole 
• 158966-66-6 2-Chloro-1-(2,4-dichloro-6-methoxy-phenyl)-1H-pyrrole 
• 171058-86-9 2,3-Dichloro-1-(2,4-dichloro-6-methoxy-phenyl)-1H-pyrrole 
• 158966-74-6 1-(2,4-Dichloro-6-methoxy-phenyl)-1H-pyrrole-2-carboxylic acid 
• 158966-76-8 4,5-Dichloro-1-(2,4-dichloro-6-methoxy-phenyl)-1H-pyrrole-2-carboxylic acid 
• 70643-29-7 8-Chlor-1,5-dihydro-6-hydroxy-1-phenyl-2H-1,5-benzodiazepin-2,4(3H)-dion 
• 74672-04-1 6-Chlor-4-hydroxy-1-phenyl-2-benzimidazolessigsaeure-ethylester 
• 74672-03-0 N-(5-Chlor-3-hydroxy-2-nitrophenyl)-N-phenyl-malonsaeure-ethylester-amid 

Relevant articles and documents

ANTIBIOTIC COMPOUNDS

The present invention relates to antibiotic compounds of formula (I), to compositions containing these compounds and to methods of treating bacterial diseases and infections using the compounds. The compounds find application in the treatment of infection with, and diseases caused by, Gram-positive and/or Gram-negative bacteria, and in particular in the treatment of infection with, and diseases caused by, Neisseria gonorrhoeae.

Synthesis of sterically hindered polychlorinated biphenyl derivatives

A series of sterically hindered (methoxylated) polychlorinated biphenyl derivatives were synthesized using the Suzuki and the Ullmann coupling reactions. The Suzuki coupling with Pd(dba)2-dicyclohexylphosphino-2,6- dimethoxybiphenyl (DPDB) gave better yields (65-98%) compared to the classic Ullmann coupling reaction (20-38%). Despite the reactive catalyst system, no significant coupling with aromatic chlorine substituents was observed. Crystal structure analysis of four PCB derivatives revealed solid state dihedral angles ranging from 69.7 to 81.0, which indicates that these highly ortho-substituted PCB derivatives have some conformational flexibility. Georg Thieme Verlag Stuttgart.

Synthesis of deuterium labelled 4'-hydroxydiclofenac

Diclofenac is a potentially useful substrate for the study of drug-drug interactions caused by modulation of the activity of specific isoforms of cytochrome P450. The synthesis of a deuterium labelled version of its principal human metabolite, 4'-hydroxydiclofenac, for use as an internal standard in LC-MS-MS studies, is described.