7471-95-6

Basic information

• Product Name: 9H-Fluorene-9-carboxylic acid amide
• Synonyms: 9H-Fluorene-9-carboxylic acid amide;9-(Aminocarbonyl)fluorene;9-Carbamoylfluorene;9H-Fluorene-9-carboxamide;Fluorene-9-carboxamide;Fluorene-9-carboxylic acid amide;9H-FLUORENE-9-CARBOXAMIDE(WXG03167)
• CAS NO: 7471-95-6
• Molecular Formula: C₁₄H₁₁NO
• Molecular Weight: 209.2432
• Mol File: 7471-95-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 252-255℃
• Boiling Point: 459.9 °C at 760 mmHg
• Flash Point: 231.9 °C
• Appearance: /
• Density: 1.254
• Vapor Pressure: 1.22E-08mmHg at 25°C
• Refractive Index: 1.664
• PKA: 15.70±0.20(Predicted)
• CAS DataBase Reference: 9H-Fluorene-9-carboxylic acid amide(CAS DataBase Reference)
• NIST Chemistry Reference: 9H-Fluorene-9-carboxylic acid amide(7471-95-6)
• EPA Substance Registry System: 9H-Fluorene-9-carboxylic acid amide(7471-95-6)

Safety Data

• Hazardous Substances Data: 7471-95-6(Hazardous Substances Data)

Usage

Uses

Fluorene-9-carboxamide is a derivative of Fluorene (F462000), which is a polycyclic aromatic hydrocarbons as micropollutants.

InChI:InChI=1/C14H11NO/c15-14(16)13-11-7-3-1-5-9(11)10-6-2-4-8-12(10)13/h1-8,13H,(H2,15,16)

Upstream product

• 86-73-7 9H-fluorene 
• 24168-51-2 9H-fluorene-9-carbonyl chloride 
• 3002-30-0 methyl 9H-fluorene-9-carboxylate 
• 75-61-6 dibromodifluoromethane 
• 70766-02-8 N-(9H-fluoren-9-ylidene)-1-phenylmethanamine 
• 1989-33-9 9H-fluorene-9-carboxylic acid 
• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 76-93-7 Benzilic acid 
• 611-73-4 Benzoylformic acid 
• 71-43-2 benzene 
• 52182-15-7 ethyl benzilate 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 1529-40-4 9H-fluorene-9-carbonitrile 
• 34577-90-7 9H-fluoren-9-ylmethanamine 
• 1989-33-9 9H-fluorene-9-carboxylic acid 
• 79156-94-8 9-aminocarbonyl-9-(2-cyanoethyl)fluorene 

Relevant articles and documents

The impact of cation structure upon the acidity of triazolium salts in dimethyl sulfoxide

A series of triazolium salts, selected for their varying electronic and steric properties, were prepared and their pKa values were determined in DMSO at 25 °C using the bracketing indicator method. The effect of each systematic structural variation upon the acidity of the triazolium cation has been considered, in particular examining the effects of systematically altering electronic properties, quantified through the use of Hammett σ parameters. The first pKa value for an azolium salt that generates a mesionic carbene is also reported. These new data allow for the selection of appropriate bases for the deprotonation of such triazolium salts and the potential to correlate the pKa values determined herein with the nucleophilicity of the corresponding carbenes.

Anti-viral method

PCT No. PCT/US97/07431 Sec. 371 Date Jan. 6, 1999 Sec. 102(e) Date Jan. 6, 1999 PCT Filed May 2, 1997 PCT Pub. No. WO97/41846 PCT Pub. Date Nov. 13, 1997The present invention provides compounds which inhibit an envelope virus by inhibiting the fusion of the virus with the host cell. The virus may be inhibited in an infected cell, a cell susceptible of infection or a mammal in need thereof.

Treating cardiac arrhythmias

Fluorenes bearing a 9-aminoalkyl substituent are useful antiarrhythmic agents. Pharmaceutical formulations containing such compounds are provided, as well as a method of treatment.