7486-95-5

Basic information

• Product Name: 3-AZA-TRICYCLO[4.2.1.0(2,5)]NONAN-4-ONE
• Synonyms: 4-OXO-3-AZA-TRICYCLO[4.2.1.0(2.5)]NONANE;3-AZA-TRICYCLO[4.2.1.0(2,5)]NONAN-4-ONE;NORBORNANE-AZETIDINONE
• CAS NO: 7486-95-5
• Molecular Formula: C₈H₁₁NO
• Molecular Weight: 137.18
• Mol File: 7486-95-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 63-66 °C
• Boiling Point: 252.03°C (rough estimate)
• Flash Point: 185.4°C
• Appearance: /
• Density: 1.0630 (rough estimate)
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.5470 (estimate)
• Storage Temp.: 0-6°C
• CAS DataBase Reference: 3-AZA-TRICYCLO[4.2.1.0(2,5)]NONAN-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AZA-TRICYCLO[4.2.1.0(2,5)]NONAN-4-ONE(7486-95-5)
• EPA Substance Registry System: 3-AZA-TRICYCLO[4.2.1.0(2,5)]NONAN-4-ONE(7486-95-5)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 7486-95-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H11NO/c10-8-6-4-1-2-5(3-4)7(6)9-8/h4-7H,1-3H2,(H,9,10)/t4-,5+,6+,7-/m0/s1

Upstream product

• 498-66-8 norborn-2-ene 
• 1189-71-5 isocyanate de chlorosulfonyle 
• 498-66-8 norbornene 
• 14932-21-9 N-(Chlorosulfonyl)-exo-3-aza-4-ketotricyclo<4.2.1.0^2,5>nonane 

Downstream Products

• 122000-85-5 (1R,2S,5R,6S)-3-Benzyl-3-aza-tricyclo[4.2.1.0^2,5]nonan-4-one 
• 113094-16-9 3-phenylcarbamoylaza-4-oxotetracyclo<4.2.1.0>nonane 
• 113094-18-1 3-(m-chlorophenyl)carbamoylaza-4-oxotetracyclo<4.2.1.0>nonane 
• 202280-02-2 (1S,2R,3S,4R)-3-exo-aminobicyclo[2.2.1]heptane-2-exo-carboxylic acid 
• 179462-35-2 (1S,2R,5S,6R)-3-azatricyclo[4.2.1.0^2,5]nonan-4-one 
• 122000-91-3 (1R,2R,5S,6R,7S)-3-Benzyl-7-hydroxy-3-aza-tricyclo[4.2.1.0^2,5]nonan-4-one 
• 113094-14-7 3-phenyl-5,8-methano-3,4,r-4a,c-5,6,7,c-8,c-8a-1H-octahydroquinazoline-2,4-dione 
• 924266-31-9 (1R,2S,5R,6S)-exo-3-azatricyclo[4.2.1.0(2,5)]nonan-4-one 
• 1071520-41-6 (1S,2R,3S,4R)-3-(4-fluoro-benzylamino)-bicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester 
• 95630-75-4 ethyl exo-3-aminobicyclo<2.2.1>heptane-2-exo-carboxylate hydrochloride 
• 105786-35-4 (rac-di-exo)-3-amino-bicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester 
• 1071520-38-1 (1R,2S,3R,4S)-3-ethoxycarbonyl-bicyclo [2.2.1]hept-2-yl-aminium (S)-α-hydroxyphenylacetate 
• 1071517-82-2 (1S,2R,3S,4R)-3-(4-fluoro-benzyl)-6-hydroxy-5-(7-iodo-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-3-yl)-3-aza-tricyclo[6.2.1.0(2,7)]undec-5-en-4-one 
• 1071517-39-9 N-{3-[(1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.0(2,7)]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}methanesulfonamide 

Relevant articles and documents

A METHOD OF INHIBITING HEPATITIS C VIRUS BY COMBINATION OF A 5,6-DIHYDRO-1H-PYRIDIN-2-ONE AND ONE OR MORE ADDITIONAL ANTIVIRAL COMPOUNDS

The invention is directed to a method of treating infections by hepatitis C virus by administering N-{3-[(1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1 -dioxo-l,4-dihydro-lλ6- benzo[l,2,4]thiadiazin-7-yl} -methanesulfonamide and one or more additional antiviral compounds or pharmaceutical compositions containing such compounds.

5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS

The invention is directed to 5,6-dihydro-lH-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.