749167-08-6Relevant articles and documents
Diastereoselective synthesis of a core fragment of ritonavir and lopinavir
Roy, Arnab,Reddy, Lekkala Amarnath,Dwivedi, Namrata,Naram, Jyothirmayi,Swapna, Rodda,Malakondaiah, Golla China,Ravikumar, Mylavarpu,Bhalerao, Dinesh,Pratap, Taduri Bhanu,Reddy, Padi Pratap,Bhattacharya, Apurba,Bandichhor, Rakeshwar
, p. 6968 - 6970 (2012/02/13)
A novel approach to the synthesis of Boc-core, a key starting material for ritonavir and lopinavir involving an unprecedented diastereoselective nitroaldol reaction on β-amino aldehyde is disclosed.
Synthesis of enantiomerically pure functionalised amides (EPC-synthesis) from chiral β-aminated organolithium intermediates
Foubelo, Francisco,Yus, Miguel
, p. 4831 - 4834 (2007/10/02)
The successive deprotonation-lithiation of chiral chloroamides 1 with n-butyllithium and lithium naphthalenide, respectively, at -78°C leads to the corresponding chiral β-aminated organolithium intermediates 2, which by reaction with different electrophil
