7498-88-6

Basic information

• Product Name: 4,4-DIPHENYL-3-BUTENOIC ACID
• Synonyms: 4,4-DIPHENYL-3-BUTENOIC ACID;4,4-DIPHENYL-BUT-3-ENOIC ACID
• CAS NO: 7498-88-6
• Molecular Formula: C₁₆H₁₄O₂
• Molecular Weight: 238.28
• Mol File: 7498-88-6.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 396.7°Cat760mmHg
• Flash Point: 293.5°C
• Appearance: /
• Density: 1.145g/cm³
• Vapor Pressure: 5.26E-07mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: 4,4-DIPHENYL-3-BUTENOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-DIPHENYL-3-BUTENOIC ACID(7498-88-6)
• EPA Substance Registry System: 4,4-DIPHENYL-3-BUTENOIC ACID(7498-88-6)

Safety Data

• Hazardous Substances Data: 7498-88-6(Hazardous Substances Data)

Usage

General Description

4,4-Diphenyl-3-butenoic acid is a synthetic organic compound with the molecular formula C18H16O2. It is a pale yellow solid that is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. 4,4-DIPHENYL-3-BUTENOIC ACID is also known for its potential antiviral and cytotoxic properties. Its structure consists of a butenoic acid group, which is a carboxylic acid with an unsaturated carbon-carbon bond. The presence of the two phenyl groups in the molecule contributes to its stability and reactivity in organic reactions. 4,4-Diphenyl-3-butenoic acid is an important intermediate in the production of various fine chemicals and has applications in the fields of pharmaceuticals, agrochemicals, and materials science.

InChI:InChI=1/C16H14O2/c17-16(18)12-11-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-11H,12H2,(H,17,18)

Upstream product

• 778-66-5 1,1-diphenyl-1-propene 
• 3003-91-6 cumyl potassium 
• 947-91-1 Diphenylacetaldehyde 
• 141-82-2 malonic acid 
• 5438-22-2 3-(ethoxycarbonyl)-4,4-diphenylbut-3-enoic acid 
• 5693-09-4 benzhydrylidene-succinic acid 
• 879089-49-3 (E)-4,4-diphenylbut-2-enoic acid 
• 23242-84-4 3-Carbomethoxy-4,4-diphenyl-3-butenoic acid 
• 14596-64-6 ethyl 2-oxo-5,5-diphenyltetrahydro-4-furancarboxylate 
• 14702-25-1 2,2-diphenyl-pentanedioic acid anhydride 
• 97634-46-3 ethyl (E)-4,4-diphenylbut-2-enoate 
• 124-38-9 carbon dioxide 
• 190603-18-0 1-((Z)-1-Ethoxy-4,4-diphenyl-buta-1,3-dienyl)-1H-benzotriazole 
• 405506-58-3 (E)-1-chloro-4,4-diphenyl-1-(phenylsulfinyl)but-3-ene-2-one 

Downstream Products

• 76694-24-1 4,4-diphenyl-3-buten-1-ol 
• 14578-67-7 4,4-diphenylbutanoic acid 
• 21034-30-0 4-bromo-5,5-diphenyl-dihydro-furan-2-one 
• 36159-76-9 4-phenyl-1-naphthol 
• 5761-80-8 4,4-diphenyl-3-buten-1-ol-1,1-d2 
• 119-61-9 benzophenone 
• 1210-39-5 3,3-diphenyl-2-propenal 
• 29555-29-1 3,3-diphenyl-2-propenyl acetate 
• 55004-95-0 5,5-diphenyl-4-penten-2-one 
• 39829-84-0 4,4-Diphenyl-but-3-enoyl chloride 
• 78250-37-0 1-Acetoxy-4-phenylnaphthalene 
• 65127-30-2 4,4-Diphenyl-but-3-enoic acid 3,3-diphenyl-allyl ester 
• 7746-94-3 5,5-diphenyldihydrofuran-2(3H)-one 
• 158660-01-6 Methyl 4,4-diphenyl-3-butenoate 

Relevant articles and documents

Highly selective production of propionic acid from lactic acid catalyzed by NaI

Propionic acid (PA), a valuable chemical widely used in the food and feed industry, is currently produced by the petrochemical industry. Selective production of PA from bio-based lactic acid (LA) is difficult due to the high activation energy of the hydroxyl group at the α position of the carboxyl group. Herein, a metal-free catalytic system for the highly selective transformation of bio-based LA to PA, which was used as the solvent to simplify the separation step, is reported using NaI as the catalyst. Under the optimal reaction conditions, a >99% yield of PA can be obtained from LA. A heat-induced radical-activated hydrogen mechanism was proposed based on the kinetic study and intermediate capture. The metal-free system can be reused five times without any loss in activity, and the PA product is easily separated. In addition, a two-step method using cellulose as the raw material to produce PA was conducted. This strategy offers a green and efficient approach to synthesize PA from biomass resources. This journal is

Method for preparing beta, gama-unsaturated carboxylic acid compound

The invention provides a method for preparing a beta, gamma-unsaturated carboxylic acid compound. The method comprises the steps of making an allylic alcohol compound of a formula 1 or a formula 2 react with formic acid in the presence of a palladium catalyst, a phosphorous ligand, acid anhydride and an organic solvent to obtain the beta, gamma-unsaturated carboxylic acid compound of a formula 3 or formula 4, wherein R1, R2 and R3 are defined in the description. Formic acid is utilized as a carboxylation reagent, and the beta, gamma-unsaturated carboxylic acid compound is low in price, safe, stable and low in toxicity; the yield is high, the operation is simple, and the economy is high; compared with an existing compounding method, the use of toxic gas carbon monoxide and/or an equivalent quantity of reactive metal reagents is avoided, and the method meets requirements for environment-friendly chemistry; in addition, the dose of catalysts is small, the reaction condition is mild, the reactant is high in conversion rate and product yield, and the method has a very good industrial prospect.

Palladium-Catalyzed ?±-Arylation of Aryl Acetic Acid Derivatives via Dienolate Intermediates with Aryl Chlorides and Bromides

To date, examples of ?±-arylation of carboxylic acids remain scarce. Using a deprotonative cross-coupling process (DCCP), a method for palladium-catalyzed ?3-arylation of aryl acetic acids with aryl halides has been developed. This protocol is applicable to a wide range of aryl bromides and chlorides. A procedure for the palladium-catalyzed ?±-arylation of styryl acetic acids is also described.