75001-84-2

Basic information

• Product Name: 3-(4-Acetyl-piperazin-1-yl)-4-fluoroaniline
• Synonyms: 3-(4-Acetyl-piperazin-1-yl)-4-fluoroaniline;1-[4-(5-amino-2-fluorophenyl)-1-piperazinyl]Ethanone
• CAS NO: 75001-84-2
• Molecular Formula: C₁₂H₁₆FN₃O
• Molecular Weight: 237.27
• Mol File: 75001-84-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 132 °C(Solv: benzene (71-43-2))
• Boiling Point: 461.2°C at 760 mmHg
• Flash Point: 232.7°C
• Appearance: /
• Density: 1.245g/cm³
• Vapor Pressure: 1.09E-08mmHg at 25°C
• Refractive Index: 1.58
• PKA: 5.43±0.10(Predicted)
• CAS DataBase Reference: 3-(4-Acetyl-piperazin-1-yl)-4-fluoroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Acetyl-piperazin-1-yl)-4-fluoroaniline(75001-84-2)
• EPA Substance Registry System: 3-(4-Acetyl-piperazin-1-yl)-4-fluoroaniline(75001-84-2)

Safety Data

• Hazardous Substances Data: 75001-84-2(Hazardous Substances Data)

Usage

General Description

3-(4-Acetyl-piperazin-1-yl)-4-fluoroaniline is a chemical compound that consists of a piperazine ring with an acetyl group attached at the 4-position and a fluorine atom attached at the 4-position of the aniline ring. It is a potential drug candidate with various pharmacological properties. 3-(4-Acetyl-piperazin-1-yl)-4-fluoroaniline has been studied for its potential use in the treatment of neurological disorders and as an antipsychotic agent. It has also been investigated for its potential as an antibacterial and antifungal agent. The structure and properties of 3-(4-Acetyl-piperazin-1-yl)-4-fluoroaniline make it a versatile compound with potential applications in the pharmaceutical industry.

InChI:InChI=1/C12H16FN3O/c1-9(17)15-4-6-16(7-5-15)12-8-10(14)2-3-11(12)13/h2-3,8H,4-7,14H2,1H3

Upstream product

• 75001-48-8 1-acetyl-4-(2-fluoro-5-nitrophenyl)piperazine 
• 75012-63-4 1-acetyl-4-(o-fluorophenyl)piperazine 
• 1011-15-0 1-(o-fluorophenyl)piperazine 
• 13889-98-0 N-acetylpiperidine 
• 367-21-5 3-chloro-4-fluorophenylamine 

Relevant articles and documents

A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts

A process for the preparation of new organosilylpoly-phosphates from the reaction of phosphorus pentoxide with a siloxane or alkyloxysilane to obtain, in solution, reagents the composition of which is [P2O5]N[SILANE], where 1 N 10 where N is a function of temperatu-re, reaction time and solvent, being applied to the modulation of cyclization reaction of N-susbtituted aminomethylenemalonates leading to quinolones or azaqui-nolones. The N-substituted aminomethylenemalonates are prepared by the reaction of anilines with dialkyl trimethylsilyloxy-methylene-malonates.