75007-92-0Relevant articles and documents
Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines: A new class of pestivirus inhibitors
Puerstinger, Gerhard,Paeshuyse, Jan,Herdewijn, Piet,Rozenski, Jef,De Clercq, Erik,Neyts, Johan
, p. 5345 - 5349 (2006)
A novel class of inhibitors of pestiviruses (5-substituted 2-phenyl-5H-imidazo[4,5-c]pyridines) is described. Modification of the substituent in position 5 resulted in analogues with high activity (EC50 1000) aga
A one-step synthesis of substituted benzo- and pyridine-fused 1H-imidazoles
Bhatt, Ashish,Kant, Ravi,Kumar, Sonu,Reddy, Yella,Sarmah, Manash P.
, (2021/11/23)
Substituted benzimidazoles and pyrimidazoles are an important group of heterocyclic aromatic organic compounds in the field of medicinal chemistry. A one-step microwave accelerated synthesis of substituted benzo- and pyridine-fused 1H-imidazoles has been described. Mechanistically, the reaction proceeds by reacting substituted 2-fluoronitrobenzene and substituted arylamine through the formation of N-hydroxy intermediate, which at higher temperature cleaves to afford the desired product. This approach achieved reductions in reaction times, higher yields, cleaner reactions than the previously described synthetic processes.
Photophysics of 2-(4′-amino-2′-hydroxyphenyl)-1H-imidazo-[4,5- c ]pyridine and its analogues: Intramolecular proton transfer versus intramolecular charge transfer
Behera, Santosh Kumar,Karak, Ananda,Krishnamoorthy
, p. 2330 - 2344 (2015/03/04)
Photophysical characteristics of 2-(4′-amino-2′-hydroxyphenyl)-1H-imidazo-[4,5-c]pyridine (AHPIP-c) have been studied in various aprotic and protic solvents using UV-visible, steady state fluorescence and time-resolved fluorescence spectroscopic technique
Selective autoxidation of benzylamines: Application to the synthesis of some nitrogen heterocycles
Nguyen, Thanh Binh,Ermolenko, Ludmila,Al-Mourabit, Ali
supporting information, p. 2713 - 2717 (2013/10/08)
A green and remarkably simple synthesis of nitrogen heterocycles from benzylamines and anilines o-substituted by a cyclizable group has been developed based on selective uncatalyzed autoxidation of benzylamines.