75059-30-2

Basic information

• Product Name: 3,5-BIS(4-METHOXYPHENYL)-1H-PYRAZOLE
• Synonyms: AKOS B022141;3,5-BIS(4-METHOXYPHENYL)-1H-PYRAZOLE
• CAS NO: 75059-30-2
• Molecular Formula: C₁₇H₁₆N₂O₂
• Molecular Weight: 280.32
• Mol File: 75059-30-2.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,5-BIS(4-METHOXYPHENYL)-1H-PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-BIS(4-METHOXYPHENYL)-1H-PYRAZOLE(75059-30-2)
• EPA Substance Registry System: 3,5-BIS(4-METHOXYPHENYL)-1H-PYRAZOLE(75059-30-2)

Safety Data

• Hazardous Substances Data: 75059-30-2(Hazardous Substances Data)

Upstream product

• 18362-51-1 1,3-bis(4'-methoxyphenyl)propane-1,3-dione 
• 94-30-4 ethyl 4-methoxybenzoate 
• 41564-67-4 (E)-1,3-bis(4-methoxyphenyl)-2-propene-1-one 
• 105782-42-1 (2RS,3SR)-2,3-epoxy-1-(4-methoxyphenyl)-3-(4-methoxyphenyl)propan-1-one 
• 563-41-7 semicarbazide hydrochloride 
• 76973-45-0 3,5-di(4-methoxyphenyl)-2-pyrazoline 
• 123-11-5 4-methoxy-benzaldehyde 
• 2373-89-9 4,4'-dimethoxychalcone 
• 100-07-2 4-methoxy-benzoyl chloride 
• 768-60-5 4-methoxyphenylacetylen 
• 65418-71-5 1,3-bis-(4-methoxyphenyl)-2-ethynyl-1-one 
• 46318-58-5 4-methoxybenzoylnitromethane 
• 5953-85-5 p-anisaldehyde hydrazone 
• 4181-97-9 phenyl 4-methoxybenzoate 

Downstream Products

• 207689-35-8 [Au(3,5-bis(4'-methoxyphenyl)pyrazolate)]3 
• 234093-22-2 1,2,5-tri-(4-anisyl)-1H-pyrazole 

Relevant articles and documents

Synthesis, structure and acetylcholinesterase inhibition activity of new diarylpyrazoles

A variety of diarylpyrazole derivatives III-VI were synthesized and structurally characterized using FTIR, 1H and 13C NMR spectroscopy, and in case of compound VIb by X-ray single crystal analysis. The in vitro biological studies rev

A highly efficient heterogeneous palladium-catalyzed cascade three-component reaction of acid chlorides, terminal alkynes and hydrazines leading to pyrazoles

In the presence of 0.5 mol% of 3-(2-aminoethylamino)propyl-functionalized MCM-41-immobilized palladium(II) complex [MCM-41-2N-Pd(OAc)2] and 1.0 mol% of CuI, acid chlorides were coupled with terminal alkynes in Et3N at 50 °C to give α,β-unsaturated ynones, which were converted in situ into pyrazoles by the cycloaddition of hydrazines at room temperature with acetonitrile as cosolvent. The cascade reactions generated a variety of pyrazole derivatives in moderate to good yields, and this heterogeneous palladium catalyst exhibited higher catalytic activity than PdCl2(PPh3)2 and could be recovered and reused for at least 10 consecutive trials without any decreases in activity.

One-pot synthesis of 3,5-diphenyl-1h-pyrazoles from chalcones and hydrazine under mechanochemical ball milling

A highly efficient and environmentally friendly method has been developed for facile synthesis of 3,5-diphenyl-1H-pyrazoles under mechanochemical ball-milling conditions. The advantages of short reaction time, high efficiency, no separation of in situ generated intermediate, using cheap sodium persulfate as the oxidant, together with very simple work-up procedure, make this one-pot and solvent-free protocol a green and powerful alternative to traditional methods for the synthesis of these kinds of compounds.