7515-16-4

Basic information

• Product Name: 2-Propynoic acid, 3-(4-Methylphenyl)-, Methyl ester
• Synonyms: 2-Propynoic acid, 3-(4-Methylphenyl)-, Methyl ester;methyl 3-(p-tolyl)propiolate;methyl 3-(4-methylphenyl)prop-2-ynoate
• CAS NO: 7515-16-4
• Molecular Formula: C₁₁H₁₀O₂
• Molecular Weight: 174.1959
• Mol File: 7515-16-4.mol
• Article Data: 28

Chemical Properties

• Melting Point: 68-69 °C
• Boiling Point: 263.7±19.0 °C(Predicted)
• Appearance: /
• Density: 1.09±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2-Propynoic acid, 3-(4-Methylphenyl)-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propynoic acid, 3-(4-Methylphenyl)-, Methyl ester(7515-16-4)
• EPA Substance Registry System: 2-Propynoic acid, 3-(4-Methylphenyl)-, Methyl ester(7515-16-4)

Safety Data

• Hazardous Substances Data: 7515-16-4(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 2227-58-9 3-(4-methylphenyl)prop-2-ynoic acid 
• 148547-94-8 methyl 2,3-dibromo-3-p-tolylpropionic acid methyl ester 
• 66076-78-6 5-p-Tolyl-2,4-dihydro-pyrazol-3-one 
• 124083-42-7 5-p-tolyl-1,2-dihydro-pyrazol-3-one 
• 201230-82-2 carbon monoxide 
• 766-97-2 4-n-methylphenylacetylene 
• 77-78-1 dimethyl sulfate 
• 28321-07-5 1-(2,2-difluorovinyl)-4-methylbenzene 
• 79-22-1 methyl chloroformate 
• 106-38-7 para-bromotoluene 
• 922-67-8 propynoic acid methyl ester 
• 459-44-9 4-methylbenzenediazonium tetrafluoroborate 
• 60512-56-3 1-(2,2-dibromovinyl)-4-methylbenzene 

Downstream Products

• 122806-31-9 E-methyl β-piperidino-p-methylcinnamate 
• 122806-30-8 E-methyl β-morpholino-p-methylcinnamate 
• 137201-70-8 E-methyl β-(N,N-diethylamino)-p-methylcinnamate 
• 781674-49-5 2-p-tolyl-pyrazolo[1,5-b]pyridazine-3-carboxylic acid methyl ester 
• 869856-36-0 6-methoxy-2-p-tolyl-pyrazolo[1,5-b]pyridazine-3-carboxylic acid methyl ester 
• 850635-29-9 methyl (E)-3-(4-methylphenyl)-3-(4-fluorosulfonyl-2,3,5,6-tetramethylphenyl)propenoate 

Relevant articles and documents

Catalytic tricarbonylation of alkynes with palladium catalysts

A novel catalytic process of introducing three CO units into alkynes by palladium-catalyzed alkoxycarbonylation was developed. Based on the fundamental studies on the behavior of organopalladium complexes, mechanisms to account for the mono- and tricarbon

Au(I) Catalyzed Synthesis of Densely Substituted Pyrazolines and Dihydropyridines via Sequential Aza-Enyne Metathesis/6π-Electrocyclization

A gold(I) autotandem catalysis protocol is reported for the de novo synthesis of densely substituted pyrazolines and dihydropyridines from the corresponding imine derivatives in a highly regioselective fashion via a one-pot aza-enyne metathesis/6π-electrocyclization sequence. The substituents on the nitrogen atom of the imine perfectly control the reaction pathways from the pivotal 1-azabutadiene intermediate; thus, carbazates were converted into pyrazolines via 6π-electrocyclization of α,β-unsaturated hydrazones, while aryl imines provided dihydropyridines via 6π-electrocyclization of 3-azahexatrienes.

Oxidant- and additive-free simple synthesis of 1,1,2-triiodostyrenes by one-pot decaroboxylative iodination of propiolic acids

A metal- and oxidant-free facile synthesis of a range of 1,1,2-triiodostryrene derivatives has been developed which utilizes a simple decarboxylative triiodination of propiolic acids using molecular iodine and sodium acetate in a one-pot manner. Electron-