7527-52-8Relevant articles and documents
Enantioselective Phenolic α-Oxidation Using H2O2 via an Unusual Double Dearomatization Mechanism
McLaughlin, Michael F.,Massolo, Elisabetta,Liu, Shubin,Johnson, Jeffrey S.
supporting information, (2019/02/14)
Feedstock aromatic compounds are compelling low-cost starting points from which molecular complexity can be generated rapidly via oxidative dearomatization. Oxidative dearomatizations commonly rely heavily on hypervalent iodine or heavy metals to provide the requisite thermodynamic driving force for overcoming aromatic stabilization energy. This article describes oxidative dearomatizations of 2-(hydroxymethyl)phenols via their derived bis(dichloroacetates) using hydrogen peroxide as a mild oxidant that intercepts a transient quinone methide. A stereochemical study revealed that the reaction proceeds by a new mechanism relative to other phenol dearomatizations and is complementary to extant methods that rely on hypervalent iodine. Using a new chiral phase-transfer catalyst, the first asymmetric syntheses of 1-oxaspiro[2.5]octa-5,7-dien-4-ones were reported. The synthetic utility of the derived 1-oxaspiro[2.5]octadienones products is demonstrated in a downstream complexity-generating transformation.
Synthesis and photopolymerization kinetics of 2-phenyl-benzodioxole
Wang, Bowen,Yang, Jinliang,Nie, Jun,Zhu, Xiaoqun
, p. 651 - 659 (2014/04/03)
In this paper, a new photocoinitiator for free radical photopolymerization, belonging to the benzodioxole (BDO) derivatives, was synthesized and characterized, and the effect of phenyl at the 2-position of BDO was estimated. The structure of PhBDO was cha
Cu(II)-impregnated sulfated MCM-41: An efficient and convenient protocol for the synthesis of 1,3-benzodioxoles
Sivakumar,Ramesh,Lalitha
experimental part, p. 91 - 93 (2011/03/23)
An efficient synthesis of 1,3-benzodioxoles was achieved from catechol with different aldehydes and ketones using Cu(II) impregnated sulfated MCM-41 as an efficient and reusable catalyst. Copyright Taylor & Francis Group, LLC.
