75321-20-9 Usage
Description
1,3-Dinitropyrene is a chemical compound that has been studied for its carcinogenic properties, particularly in newborn female rats. It is known for its potential applications in various fields, including the modification of the umu-assay and the in vitro synthesis of certain compounds.
Uses
1. Used in Research and Development:
1,3-Dinitropyrene is used as a research compound for the modification of the umu-assay (ISO 13829), which is a method to assess the cytotoxic potential of toxins in vitro. This application helps in understanding the effects of various substances on cellular health and their potential harmful effects.
2. Used in Chemical Synthesis:
1,3-Dinitropyrene is also used as a synthetic compound in the in vitro synthesis of 1,N6-etheno-2′-deoxyadenosine and 1,N2-etheno-2′-deoxyguanosine. These synthesized compounds are important for studying the effects of DNA adducts and their role in genetic mutations and related diseases.
3. Used in Toxicology and Carcinogenicity Studies:
The carcinogenicity of 1,3-dinitropyrene has been studied in newborn female rats, providing valuable information on the potential health risks associated with exposure to this compound. This research contributes to the understanding of the mechanisms of carcinogenesis and the development of strategies to mitigate the risks associated with exposure to carcinogenic substances.
Safety Profile
Suspected carcinogen
with experimental carcinogenic data.
Mutation data reported. When heated to
decomposition it emits toxic fumes of NOx
Check Digit Verification of cas no
The CAS Registry Mumber 75321-20-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,3,2 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 75321-20:
(7*7)+(6*5)+(5*3)+(4*2)+(3*1)+(2*2)+(1*0)=109
109 % 10 = 9
So 75321-20-9 is a valid CAS Registry Number.
InChI:InChI=1/C16H8N2O4/c19-17(20)13-8-14(18(21)22)12-7-5-10-3-1-2-9-4-6-11(13)16(12)15(9)10/h1-8H
75321-20-9Relevant articles and documents
Preparation of Pure Isomers of Dinitropyrenes
Hashimoto, Yuichi,Shudo, Koichi
, p. 1992 - 1994 (2007/10/02)
Isomers of dinitripyrenes (1,3-, 1,6-, and 1,8-dinitripyrenes) uncontamined by the other isomers were prepared from the corresponding diaminopyrenes by oxidation, or nucleophilic substitution with nitrite after diazotization.Keywords: dinitropyrene; 1,3-dinitropyrene; 1,6-dinitropyrene; 1,8-dinitropyrene; diaminopyrene; preparation of nitroarenes.
