75351-33-6

Basic information

• Product Name: 1,6-Hexanediol, mono(4-methylbenzenesulfonate)
• CAS NO: 75351-33-6
• Molecular Formula: C13H20O4S
• Molecular Weight: 272.365
• Mol File: 75351-33-6.mol
• Article Data: 29

Chemical Properties

• CAS DataBase Reference: 1,6-Hexanediol, mono(4-methylbenzenesulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-Hexanediol, mono(4-methylbenzenesulfonate)(75351-33-6)
• EPA Substance Registry System: 1,6-Hexanediol, mono(4-methylbenzenesulfonate)(75351-33-6)

Safety Data

• Hazardous Substances Data: 75351-33-6(Hazardous Substances Data)

Upstream product

• 629-11-8 1,6-hexanediol 
• 98-59-9 p-toluenesulfonyl chloride 
• 173470-74-1 (hex-5-en-1-yloxy)triisopropylsilane 
• 307965-12-4 1,6-hexanediol monoacetate p-toluenesulfonyl ester 
• 63294-76-8 6-<(tetrahydro-2H-pyran-2-yl)oxy>hexyl toluene-4-sulfonate 

Downstream Products

• 122887-99-4 6-oxohexyl(4-methylbenzene)sulfonate 
• 299205-80-4 4-methylbenzenesulfonic acid, 6-(methoxymethoxy)hexyl ester 
• 16654-54-9 6-phenoxyhexan-1-ol 
• 847232-73-9 diphenyl-acetic acid 6-(toluene-4-sulfonyloxy)-hexyl ester 
• 870537-14-7 6-(tosyloxy)hexyl pivalate 
• 116748-67-5 2-<(6-hydroxyhexyl)oxy>benzaldehyde 
• 133080-87-2 4-Bromo-1-(6-hydroxyhexan-1-yloxy)benzene 
• 123-35-3 7-methyl-3-methene-1,6-octadiene 

Relevant articles and documents

Chemoselective Cleavage of Si-C(sp3) Bonds in Unactivated Tetraalkylsilanes Using Iodine Tris(trifluoroacetate)

Organosilanes are synthetically useful reagents and precursors in organic chemistry. However, the typical inertness of unactivated Si-C(sp3) bonds under conventional reaction conditions has hampered the application of simple tetraalkylsilanes in organic synthesis. Herein we report the chemoselective cleavage of Si-C(sp3) bonds of unactivated tetraalkylsilanes using iodine tris(trifluoroacetate). The reaction proceeds smoothly under mild conditions (-50 °C to room temperature) and tolerates various polar functional groups, thus enabling subsequent Tamao-Fleming oxidation to provide the corresponding alcohols. NMR experiments and density functional theory calculations on the reaction indicate that the transfer of alkyl groups from Si to the I(III) center and the formation of the Si-O bond proceed concertedly to afford an alkyl-λ3-iodane and silyl trifluoroacetate. The developed method enables the use of unactivated tetraalkylsilanes as highly stable synthetic precursors.

A metal-free reductive N-alkylation of indoles with aldehydes

A simple metal-free method has been developed for the reductive N-alkylation of indoles employing aldehydes as the alkylating agent and inexpensive Et3SiH as the reductant. A wide range of aromatic and aliphatic aldehydes are viable substrates along with

Stereoselective, Multicomponent Approach to Quaternary Substituted Hydroindole Scaffolds

The Amaryllidaceae alkaloids have been a target of synthesis for decades due to their complex architectures and biological activity. A central feature of these natural product cores is a quaternary substituted hydroindole heterocycle. Building off the fou