754214-36-3 Usage
General Description
2-(4-Tert-butylphenyl)-5-(chloromethyl)-1,3,4-oxadiazole is a chemical compound with the molecular formula C14H15ClN2O. It is a heterocyclic compound containing an oxadiazole ring, and its structure includes a tert-butylphenyl group and a chloromethyl group. 2-(4-TERT-BUTYLPHENYL)-5-(CHLOROMETHYL)-1,3,4-OXADIAZOLE has been studied for its potential use in pharmaceuticals, pesticides, and materials science. It has shown promise as a potential drug candidate for the treatment of various diseases and has also been investigated for its antimicrobial and insecticidal properties. Its unique chemical structure makes it a valuable building block for the synthesis of other organic compounds with potential biological activity.
Check Digit Verification of cas no
The CAS Registry Mumber 754214-36-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,5,4,2,1 and 4 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 754214-36:
(8*7)+(7*5)+(6*4)+(5*2)+(4*1)+(3*4)+(2*3)+(1*6)=153
153 % 10 = 3
So 754214-36-3 is a valid CAS Registry Number.
754214-36-3Relevant articles and documents
Synthesis and antimicrobial properties of 1,3,4-oxadiazole analogs containing dibenzosuberane moiety
Moger, Manjunath,Satam, Vijay,Govindaraju, Darshan Raj C.,Paniraj,Gopinath, Vadiraj S.,Hindupur, Rama Mohan,Pati, Hari N.
, p. 104 - 111 (2014/02/14)
A series of ten novel 1,3,4-oxadiazole analogs containing dibenzosuberane moiety were synthesized using linear as well as convergent synthesis approach. All the compounds were characterized by mass spectrometry, infrared (IR), 1H and 13C nuclear magnetic resonance (1H NMR and 13C NMR) spectroscopies and elemental analysis. These compounds were evaluated for antibacterial and antifungal activities. Among ten analogs, four compounds, namely, 8a, 8d, 8e and 8j were found to be highly active antibacterial and antifungal agents.
Microwave-assisted one-step synthesis of substituted 2-chloromethyl-1,3,4- oxadiazoles
Natero, Reina,Koltun, Dmitry O.,Zablocki, Jeffery A.
, p. 2523 - 2529 (2007/10/03)
We have developed a simple one-step synthesis of 2-chloromethyl-1,3,4- oxadiazoles from commercially available acylhydrazides using 1-chloro-2,2,2-trimethoxyethane as a solvent under microwave irradiation.
