755031-80-2

Basic information

• Product Name: 5-chloro-2-iodo-4-methylaniline
• Synonyms: 5-chloro-2-iodo-4-methylaniline;5-Chloro-2-iodo-4-methyl-phenylamine
• CAS NO: 755031-80-2
• Molecular Formula: C₇H₇ClIN
• Molecular Weight: 267.49465
• Mol File: 755031-80-2.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-chloro-2-iodo-4-methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-iodo-4-methylaniline(755031-80-2)
• EPA Substance Registry System: 5-chloro-2-iodo-4-methylaniline(755031-80-2)

Safety Data

• Hazardous Substances Data: 755031-80-2(Hazardous Substances Data)

Upstream product

• 114971-52-7 N,N,N-trimethylbenzenemethanaminium dichloroiodate 
• 95-74-9 3-chloro-p-toluidine 

Downstream Products

• 755031-82-4 methyl 2-(acetylamino)-4-chloro-5-methylbenzoate 
• 1589522-77-9 methyl 3-benzyl-6-chloro-5-methyl-1H-indole-2-carboxylate 
• 181632-25-7 SB 242084 
• 162100-42-7 6-chloro-5-methyl-1H-indole 
• 162100-44-9 6-chloro-5-methyl-2,3-dihydro-1H-indole 

Relevant articles and documents

New Indolo[3,2-b]indole based small organic molecules for Organic Thin Film Transistors (OTFTs): A combined experimental and DFT Study

Synthesis of new indolo[3,2-b]indoles (5a- 5j) in presence of Ag-doped ZnO and (Diacetoxyiodo) benzene system under visible-light have been reported. All the new fused linear heterocyclic indolo[3,2-b]indole systems (5a- 5j) thoroughly characterized by spectroscopic methods like mass, UV-visible, NMR and C, H, N elemental analysis. Further, their photophysical properties were carried out by combined experimental and theoretical studies. Thermogravimetric studies are carried out to confirm the thermal stability of molecules. The frontier molecular orbitals of molecules are characterized with the help of cyclic voltammetry. Additionally, the compounds of series 5 were used for the fabrication of organic thin-film transistors, which indicated the hole mobilities in the range of 0.11 – 0.85 cm2/Vs and with on/off ratio 105 on ODTS-SiO2 substrate at 50 °C and are also supported by DFT studies.

NEW COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES

This invention provides novel compounds and the novel compounds for use as a medicine, more in particular for the prevention or treatment of neurodegenerative disorders, more specifically certain neurological disorders, such as disorders collectively known as tauopathies, and disorders characterised by cytotoxic α-synuclein amyloidogenesis. The present invention also relates to the use of said novel compounds for the manufacture of medicaments useful for treating such neurodegenerative disorders. The present invention further relates to pharmaceutical compositions including said novel compounds and to methods for the preparation of said novel compounds. The compounds have the formula (A1) wherein R1, R2, R4, R6, E, n, Y1, Y2, Y3, Y4, Y5, L, B, R8, and m are as defined in the claims.

NOVEL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES

This invention provides novel compounds and the novel compounds for use as a medicine, more in particular for the prevention or treatment of neurodegenerative disorders, more specifically certain neurological disorders, such as disorders collectively known as tauopathies, and disorders characterised by cytotoxic α-synuclein amyloidogenesis. The present invention also relates to the use of said novel compounds for the manufacture of medicaments useful for treating such neurodegenerative disorders. The present invention further relates to pharmaceutical compositions including said novel compounds and to methods for the preparation of said novel compounds. The compounds have the formula (A1), wherein R1, R2, R4, R5, R6, E, n, Y1, Y2, Y3, Y4, Y5, B, R8, and m are as defined in the claims.