756859-05-9

Basic information

• Product Name: 1-[[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL]PIPERAZINE
• Synonyms: 1-[[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL]PIPERAZINE
• CAS NO: 756859-05-9
• Molecular Formula: C₁₁H₁₃F₃N₂O₃S
• Molecular Weight: 310.29
• Mol File: 756859-05-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-[[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL]PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL]PIPERAZINE(756859-05-9)
• EPA Substance Registry System: 1-[[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL]PIPERAZINE(756859-05-9)

Safety Data

• Hazardous Substances Data: 756859-05-9(Hazardous Substances Data)

Usage

Chemical structure

Piperazine derivative with a sulfonamide functional group attached to a phenyl ring containing a trifluoromethoxy substituent.

Application

Used in the synthesis of pharmaceutical drugs.

Potential uses

Studied for its potential as an antipsychotic and anticonvulsant medication.

Mechanism of action

Ability to interact with serotonin and dopamine receptors in the brain.

Target disorders

Potential candidate for treating various psychiatric and neurological disorders.

Research and development

Unique structure and functional groups make it a promising target for further research and development in the pharmaceutical industry.

Upstream product

• 847039-26-3 1,1-dimethylethyl 4-({4-[(trifluoromethyl)oxy]phenyl}sulfonyl)-1-piperazinecarboxylate 
• 94108-56-2 4-(trifluoro-methoxy)benzene-1-sulfonyl chloride 
• 110-85-0 piperazine 

Downstream Products

• 1204925-64-3 3-{[4-({4-[(trifluoromethyl)oxy]phenyl}sulfonyl)-1-piperazinyl]carbonyl}pyrazolo[1,5-a]pyrimidine 
• 1233940-78-7 7-((4-(4-(trifluoromethoxy)phenylsulfonyl)piperazin-1-yl)methyl)quinolin-8-ol 
• 1342253-49-9 8-methyl-7-{[4-({4-[(trifluoromethyl)oxy]phenyl}sulfonyl)-1-piperazinyl]carbonyl}quinoline 

Relevant articles and documents

Synthesis and antibacterial activity of novel myricetin derivatives containing sulfonylpiperazine

Myricetin derivatives containing sulfonylpiperazine were synthesized and their structures were confirmed by NMR and HRMS. The antibacterial activity results indicated that some compounds showed good antibacterial activity against Xanthomonas oryzaepv. ory

Sulfonylpiperazines based on a flavone as antioxidant and cytotoxic agents

Chrysin-based sulfonylpiperazines 7a-k were synthesized and investigated for their in vitro free radical scavenging potential as well as cytotoxic efficacies against selected cancer cell lines. Cytotoxicity of the new compounds toward noncancer cells was

PIPERAZINE DERIVATIVES FOR BLOCKING Cav2.2 CALCIUM CHANNELS

The present invention relates to novel piperazine compounds; to pharmaceutical compositions containing the compounds; and to the use of the compounds in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial and to treat diseases for which blocking the Cav2.2 and Cav3.2 calcium channels is beneficial, e.g. to treat pain.