94108-56-2

Basic information

• Product Name: 4-(Trifluoromethoxy)benzenesulfonyl chloride
• Synonyms: 4-TRIFLUOROMETHOXYPHENYL-SULFONYLCHLORIDE;BUTTPARK 21\07-19;p-(trifluoromethoxy)benzenesulphonyl chloride;4-(Trifluoromethoxy)benzenesulphonyl chloride 98%;4-(Trifluoromethoxy)benzenesulphonylchloride98%;4-(Trifluoromethoxy)benzensulphonyl chloride;4-(Trifluoromethoxy)benzenesulfonyl chloride,98%;{[4-(trifluoroMethoxy)benzene]sulfonyl}chloranuide
• CAS NO: 94108-56-2
• Molecular Formula: C₇H₄ClF₃O₃S
• Molecular Weight: 260.62
• EINECS: 302-397-9
• Product Categories: Benzenesulfonyl chloride;Miscellaneous;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds;Building Blocks;Chemical Synthesis;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds;Fluorine series
• Mol File: 94108-56-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 120-122 °C (15 mmHg)
• Flash Point: >230 °F
• Appearance: Clear colorless to pale yellow liquid
• Density: 1.536 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.23 psi ( 20 °C)
• Refractive Index: n20/D 1.479(lit.)
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive: Moisture Sensitive
• BRN: 7641524
• CAS DataBase Reference: 4-(Trifluoromethoxy)benzenesulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Trifluoromethoxy)benzenesulfonyl chloride(94108-56-2)
• EPA Substance Registry System: 4-(Trifluoromethoxy)benzenesulfonyl chloride(94108-56-2)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45-39-37-36
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 94108-56-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H4ClF3O3S/c8-15(12,13)6-3-1-5(2-4-6)14-7(9,10)11/h1-4H

Upstream product

• 139301-27-2 4-trifluoromethoxyphenylboronic acid 

Downstream Products

• 909520-99-6 N-(4-iodo-phenyl)-4-trifluoromethoxy-benzenesulfonamide 

Relevant articles and documents

Synthesis of aryl sulfonamides via palladium-catalyzed chlorosulfonylation of arylboronic acids

A palladium-catalyzed method for the preparation of sulfonamides is described. The process exhibits significant functional group tolerance and allows for the preparation of a number of arylsulfonyl chlorides and sulfonamides under mild conditions.

Keratinocyte growth inhibitors and hydroxamic acid derivatives

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