7597-73-1

Basic information

• Product Name: N-(1-bromo-2-naphthyl)acetamide
• Synonyms: N-(1-bromo-2-naphthyl)acetamide;acetamide, N-(1-bromo-2-naphthalenyl)-
• CAS NO: 7597-73-1
• Molecular Formula: C₁₂H₁₀BrNO
• Molecular Weight: 264.1179
• Mol File: 7597-73-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 448.3 °C at 760 mmHg
• Flash Point: 224.9 °C
• Appearance: /
• Density: 1.528 g/cm³
• Vapor Pressure: 3.14E-08mmHg at 25°C
• Refractive Index: 1.69
• CAS DataBase Reference: N-(1-bromo-2-naphthyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-bromo-2-naphthyl)acetamide(7597-73-1)
• EPA Substance Registry System: N-(1-bromo-2-naphthyl)acetamide(7597-73-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 7597-73-1(Hazardous Substances Data)

Usage

General Description

N-(1-bromo-2-naphthyl)acetamide is a chemical compound with the molecular formula C14H12BrNO. This chemical compound falls into the category of organic compounds known as naphthalenes, which are structures containing a naphthalene moiety, which is a polycyclic aromatic hydrocarbon made up of two fused benzene rings. The properties of N-(1-bromo-2-naphthyl)acetamide include a heavy atom count of 17, a hydrogen bond donor count of 1 and a hydrogen bond acceptor count of 1. As a brominated acetamide derivative of naphthalene, it has different potential applications which can range from biological to material science research. Specific information on toxicity, ecological information, or applications of this compound should typically be obtained from detailed product or safety data sheets.

InChI:InChI=1/C12H10BrNO/c1-8(15)14-11-7-6-9-4-2-3-5-10(9)12(11)13/h2-7H,1H3,(H,14,15)

Upstream product

• 77-48-5 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione 
• 581-97-5 2-acetylaminonaphthalene 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 
• 91-59-8 naphthalen-2-ylamine 
• 20191-75-7 1-bromo-2-naphthylamine 
• 108-24-7 acetic anhydride 
• 2508-23-8 N-Hydroxy-2-acetylaminonaphthalin 

Downstream Products

• 20191-75-7 1-bromo-2-naphthylamine 
• 64574-27-2 N-(1,8-dinitro-[2]naphthyl)-acetamide 
• 7066-11-7 N-(1-bromo-[2]naphthyl)-diacetamide 
• 6329-24-4 2-acetoaminonaphthalene-1-carbonitrile 
• 109297-28-1 2-Chloronaphthalene-1-carbonitrile 
• 109297-21-4 2--1-tolylsulphonyl-1a,7b-dihydro-1H-cyclopropanaphthalene-3-carbonitrile 
• 85-02-9 benzo[f]quinoline 
• 342-55-2 1-bromo-2-fluoro-naphthalene 
• 85-01-8 phenanthrene 

Relevant articles and documents

Nickel(II)- And Silver(I)-Catalyzed C-H Bond Halogenation of Anilides and Carbamates

ortho -C-H bond halogenation of anilides and N -aryl carbamates using easily available N -halosuccinimides (NXS) as the active halogenation reagent in the presence of nickel or silver catalyst has been developed. This method provides a new approach to 2-haloanilides and carbamates, which may serve as starting materials for the synthesis of pharmaceutically and biologically active compounds.

A Simple Synthesis of Phenanthrene

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Synthesis of polycyclic aminocyclobutane systems by the rearrangement of N-(ortho-Vinylphenyl) 2-Azabicyclo[3.1.0]hexane derivatives

The acid-catalysed thermal rearrangements of a family of N-aryl 2-azabicyclo[3.1.0]hexanes is described. These substrates, designed in such a way that the aromatic system is conjugated with an alkene group located at the ortho position relative to the nitrogen atom, have been prepared by using an intramolecular Kulinkovich-de Meijere reaction. The rearrangements can then be conducted either under standard thermal conditions or with microwave activation. Depending on the conditions applied and the substitution pattern, dihydroquinoline or polycyclic aminocyclobutane derivatives can be obtained. A mechanistic discussion is provided, with the proposition of the initial protonation of the aminocyclopropane moiety to give an iminium intermediate. By analogy with related intermolecular reactions, the involvement of electrocyclic reactions among the series of elementary steps that follow is put forward. Small rings: The acid-catalysed rearrangement of bicyclic N-aryl aminocyclopropanes with an alkene group located at the ortho position, either under standard thermal conditions or with microwave activation, is described (see scheme). The method provides access to dihydroquinoline and polycyclic aminocyclobutane derivatives. By analogy with related intermolecular reactions, the involvement of an electrocyclic reaction is proposed. Copyright