76029-42-0

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-(2-cyclohexen-1-yloxy)-
• CAS NO: 76029-42-0
• Molecular Formula: C14H13NO3
• Molecular Weight: 243.262
• Mol File: 76029-42-0.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-(2-cyclohexen-1-yloxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-(2-cyclohexen-1-yloxy)-(76029-42-0)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-(2-cyclohexen-1-yloxy)-(76029-42-0)

Safety Data

• Hazardous Substances Data: 76029-42-0(Hazardous Substances Data)

Usage

Structure

Cyclic organic compound with a heterocyclic ring structure

Components

Contains 2-cyclohexen-1-yloxy group attached to isoindoline-1,3-dione core

Usage

Used in the synthesis of various pharmaceuticals and organic compounds

Biological activities

Has potential biological activities

Synthesis applications

Can be used as a starting material for the synthesis of other complex organic molecules

Fields of application

May have applications in medicinal chemistry and drug discovery.

Upstream product

• 524-38-9 N-hydroxyphthalimide 
• 822-67-3 Cyclohex-2-enol 
• 110-83-8 cyclohexene 
• 1521-51-3 rac-3-bromocyclohexene 

Downstream Products

• 54488-64-1 O-cyclohexylhydroxylamine hydrochloride 
• 169956-61-0 2-(cyclohexyloxy)-1H-isoindole-1,3(2H)-dione 
• 78730-62-8 C₆H₁₁NO*ClH 
• 360073-71-8 N-benzyl-O-(2-cyclohexenyl)hydroxylamine 
• 76029-48-6 O-(2-cyclohexenyl)hydroxylamine 

Relevant articles and documents

A new and efficient heterogeneous system for the phthalimide N-oxyl (PINO) radical generation

Sodium periodate/wet silica gel in the presence of dichloromethane is an efficient reagent at room temperature for the phthalimide N-oxyl (PINO) radical generation from its precursor N-hydroxyphthalimide (NHPI). PINO reactions with cycloalkenes occur excl

Rhodium(III)-catalyzed alkenyl c-H functionalization to dienes and allenes

An oxyacetamide-directed Rh(III)-catalyzed Z-type alkenyl C-H functionalization through a rare exo-rhodacyle intermediate is described, forming multisubstituted dienes and allenes. A variety of alkenes and propargylic carbonate coupling partners are suita

NBu4NI-catalyzed intermolecular C-O cross-coupling reactions: Synthesis of alkyloxyamines

A practical and simple nBu4NI-catalyzed C-O bond formation for the synthesis of alkyloxyamines was achieved under metal-free conditions. The reaction is applicable to the coupling of a range of benzylic and allylic hydrocarbons with N-hydroxyphthalimide and is tolerant of various functional groups. The reaction mechanism was primarily investigated and a radical process was proposed.

Organocatalytic Radical Involved Oxidative Cross-Coupling of N-Hydroxyphthalimide with Benzylic and Allylic Hydrocarbons

The cross-coupling reaction between N-hydroxyphthalimide and various benzylic and allylic hydrocarbons was realized through an organocatalytic radical-mediated process involving C(sp3)-O bond formation using tert-butyl hydroperoxide (t-BuOOH) as an oxidant and tetra-n-butylammonium iodide [(n-Bu]4NI] as a catalyst, during which the phthalimide N-oxyl (PINO) radical and benzylic and allylic radicals were generated in situ and underwent the selective radical/radical cross-coupling reaction. This novel method provides a convenient metal-free approach to the synthesis of O-alkylated hydroxy imides under mild reaction conditions.