7606-79-3

Basic information

• Product Name: AC-GLY-NHME
• Synonyms: N-ALPHA-ACETYL-GLYCINE N-METHYLAMIDE;2-(Acetylamino)-N-methyl-acetamide;Acetylglycine,N-methylamide;N-Acetylglycine N-methyl amide;AC-GLY-NHME;AC-GLYCINE-NHME;ACETYL-GLYCINE METHYL AMIDE;acetylglycyl-N-methylamide
• CAS NO: 7606-79-3
• Molecular Formula: C5H10N2O2
• Molecular Weight: 130.15
• Mol File: 7606-79-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 425.8 °C at 760 mmHg
• Flash Point: 215.8 °C
• Appearance: /
• Density: 1.058 g/cm³
• Vapor Pressure: 1.86E-07mmHg at 25°C
• Refractive Index: 1.44
• Storage Temp.: Store at 0-5°C
• CAS DataBase Reference: AC-GLY-NHME(CAS DataBase Reference)
• NIST Chemistry Reference: AC-GLY-NHME(7606-79-3)
• EPA Substance Registry System: AC-GLY-NHME(7606-79-3)

Safety Data

• Hazardous Substances Data: 7606-79-3(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Purification Methods

Recrystallise the amide from EtOH/Et2O mixture. Also recrystallise it twice from EtOAc/EtOH (16:1) and once from EtOAc. [Applewhite & Niemann J Am Chem Soc 81 2212 1959.]

InChI:InChI=1/C5H10N2O2/c1-4(8)7-3-5(9)6-2/h3H2,1-2H3,(H,6,9)(H,7,8)

Upstream product

• 72952-59-1 aceturoyl chloride 
• 74-89-5 methylamine 
• 1906-82-7 ethyl acetamidoacetate 
• 1117-77-7 methyl N-acetylglycinate 
• 556-33-2 glycine-glycine-glycine 
• 21855-72-1 N-[benzyloxycarbonyl]-N'-methyl-glycinamide 
• 108-24-7 acetic anhydride 
• 24474-93-9 2-methyl-4H-oxazol-5-one 

Relevant articles and documents

Adamantyl amino acid as γ-turn inducer for peptide

The structures of six peptide mimics having different bulkiness and/or rigidity of the amino acids were investigated spectroscopically. Comparison of H NMR, IR spectra and H-D exchangerate of the amide protons reveals that 2-amino-2-carboxyadamantane induces the high population of γ-turn conformation in the room temperature region and may be utilized as a promising γ-turn inducer for synthetic peptides.

Aqueous Solutions Containing Amino Acids and Peptides. Part 16. --Solute-Solute Interactions in Solutions Containing some N-Acetyl-N'-methylamino Acid Amides

The energetics of the interactions occuring between some N-acetyl-N'-methylamino acid amides in aqueous solutions at 25 deg C have been investigated.Osmotic coefficients and enthalpies of dilution have been obtained for single-component and two-component