76101-37-6

Basic information

• Product Name: C₆₅H₈₉N₈O₁₃PSi₃
• Synonyms: C₆₅H₈₉N₈O₁₃PSi₃
• CAS NO: 76101-37-6
• Molecular Weight: 1305.7
• Mol File: 76101-37-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₆₅H₈₉N₈O₁₃PSi₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₆₅H₈₉N₈O₁₃PSi₃(76101-37-6)
• EPA Substance Registry System: C₆₅H₈₉N₈O₁₃PSi₃(76101-37-6)

Safety Data

• Hazardous Substances Data: 76101-37-6(Hazardous Substances Data)

Upstream product

• 69504-15-0 2',3'-O,O-bis(t-butyldimethylsilyl)adenosine 
• 3279-26-3 methyl dichlorophosphite 
• 72409-30-4 N⁴-benzoyl-2'-O-(tert-butyldimethylsilyl)-5'-O-(4-monomethoxytrityl)cytidine 

Downstream Products

• 2382-66-3 Cytidin-(3',5')-adenosin 

Relevant articles and documents

The chemical synthesis of oligoribonucleotides. IX. A comparison of protecting groups in the dichloridite procedure

A series of phosphorodichloridites has been prepared incorporating the most commonly used phosphate protecting groups in oligonucleotide synthesis.The groups incude trichloroethyl, tribromoethyl, cyanoethyl, benzyl, methyl, p-chlorophenyl, and nitrophenetyl.The trichloroethyl and the nitrophenethyl appear to be the most stable groups while the cyanoethyl and methyl offer specific advantages.The benzyl and p-chlorophenyl groups are subject to limitations on their utility.Condensations can be carried out in a range of solvents incuding THF, pyridine, and DMF and at temperatures from -78 deg C to 20 deg C with a slight drop in yield with increasing temperature, at least for dinucleotide condensations.