2382-66-3

Basic information

• Product Name: ADENYLYL(3'>5')CYTIDINE FREE ACID
• Synonyms: 3'-Cytidylic acid 5'-adenosyl ester;5'-Adenylic acid 3'-cytidyl ester;5'-O-(3'-Cytidylyl)adenosine;Dinucleotide CpA;ADENYLYL(3'>5')CYTIDINE FREE ACID;cytidylyladenosine;5')cytidine free acid;cytidylyl(3'->5')adenosine
• CAS NO: 2382-66-3
• Molecular Formula: C₁₉H₂₅N₈O₁₁P
• Molecular Weight: 492.44266
• EINECS: 219-187-7
• Product Categories: Nucleotides and Nucleic Acids
• Mol File: 2382-66-3.mol
• Article Data: 7

Chemical Properties

• Melting Point: 173-175 °C
• Boiling Point: 993.2°Cat760mmHg
• Flash Point: 554.5°C
• Appearance: /
• Density: 2.23g/cm³
• Storage Temp.: −20°C
• PKA: 1.37±0.50(Predicted)
• CAS DataBase Reference: ADENYLYL(3'>5')CYTIDINE FREE ACID(CAS DataBase Reference)
• NIST Chemistry Reference: ADENYLYL(3'>5')CYTIDINE FREE ACID(2382-66-3)
• EPA Substance Registry System: ADENYLYL(3'>5')CYTIDINE FREE ACID(2382-66-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 2382-66-3(Hazardous Substances Data)

Usage

General Description

Adenylyl(3'>5')cytidine free acid is a chemical compound that belongs to the class of nucleotides and nucleosides. It is a modified form of cytidine with an adenosine monophosphate (AMP) group attached at the 3' position of the ribose ring. This modification plays a crucial role in various cellular processes, especially in the regulation of gene expression and protein synthesis. Adenylyl(3'>5')cytidine free acid is involved in signaling pathways, where it acts as a second messenger to transmit signals within cells. It is also being investigated for its potential therapeutic applications in cancer treatment and as a modulator of immune response. Further research is needed to fully understand the biological functions and potential clinical applications of this chemical compound.

Upstream product

• 633-90-9 cytidine 2',3'-cyclic monophosphate 
• 58-61-7 adenosine 
• 78092-50-9 C₈₉H₇₅ClN₉O₁₉P 
• 72624-28-3 C₄₆H₇₂Cl₃N₈O₁₂PSi₃ 
• 29886-19-9 2',3'-di-O-acetyladenosine 
• 69504-15-0 2',3'-O,O-bis(t-butyldimethylsilyl)adenosine 
• 72599-85-0 C₆₆H₈₈Cl₃N₈O₁₃PSi₃ 
• 76101-36-5 C₇₀H₉₀ClN₈O₁₃PSi₃ 
• 76101-37-6 C₆₅H₈₉N₈O₁₃PSi₃ 
• 72409-30-4 N⁴-benzoyl-2'-O-(tert-butyldimethylsilyl)-5'-O-(4-monomethoxytrityl)cytidine 
• 1177254-63-5 5'-CAGUCA-3' 
• 1177254-64-6 5'-CGAGCA-3' 

Downstream Products

• 633-90-9 cytidine 2',3'-cyclic monophosphate 
• 58-61-7 adenosine 
• 84-52-6 cytidine 3'-monophosphate 
• 85-94-9 cytidine-2'-monophosphate 

Relevant articles and documents

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Base moiety selectivity in cleavage of short oligoribonucleotides by di- and tri-nuclear Zn(II) complexes of azacrown-derived ligands

Cleavage of 6-mer oligoribonucleotides by the dinuclear Zn2+ complex of 1,3-bis[(1,5,9-triazacyclododecan-3-yl)oxymethyl]benzene (L 1) and the trinuclear Zn2+ complex of 1,3,5-tris[(1,5,9- triazacyclododecan-3-yl)oxymethyl

An Improved Method for the Application of the 4-Methoxybenzyl Group to Protect the 2'-Hydroxyl Group in the Ribonucleotide Synthesis by TFA-acidolysis

The cleavage of the 4-methoxybenzyl group from the 2'-OH-position of ribonucleosides by the hydrogenation with different Pd-catalysts as well as trifluoroacetic acid has been studied in detail.During hydrogenation, side reactions at the base residue of cytidine occurred which, however, could be extensively suppressed by PdCl2 catalysis.More practicable results were obtained with trifluoroacetic acid in the presence of cation scavengers, allowing smoothly to convert a series of 2'-methoxybenzyl ribonucleotides to the homogeneous deprotection products.