78092-50-9

Basic information

• Product Name: C₈₉H₇₅ClN₉O₁₉P
• Synonyms: C₈₉H₇₅ClN₉O₁₉P
• CAS NO: 78092-50-9
• Molecular Weight: 1641.05
• Mol File: 78092-50-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₈₉H₇₅ClN₉O₁₉P(CAS DataBase Reference)
• NIST Chemistry Reference: C₈₉H₇₅ClN₉O₁₉P(78092-50-9)
• EPA Substance Registry System: C₈₉H₇₅ClN₉O₁₉P(78092-50-9)

Safety Data

• Hazardous Substances Data: 78092-50-9(Hazardous Substances Data)

Upstream product

• 58463-04-0 N6,N6,2'-O,3'-O-tetrabenzoyladenosine 
• 78462-57-4 Phosphoric acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 5-chloro-quinolin-8-yl ester; compound with pyridine 

Downstream Products

• 78077-30-2 C₆₈H₅₇ClN₉O₁₇P 
• 2382-66-3 Cytidin-(3',5')-adenosin 

Relevant articles and documents

4-CHLOROPHENYL 5-CHLORO-8-QUINOLYL PHOSPHOROCHLORIDATE: A PRACTICALLY USEFUL PHOSPHORYLATING AGENT FOR OLIGORIBONUCLEOTIDE SYNTHESIS VIA PHOSPHOTRIESTER APPROACH

5'-O-Dimethoxytrityl-2'-O-tetrahydropyranylnucleosides (2) smoothly reacts with 4-chlorophenyl 5-chloro-8-quinolyl phosphorochloridate (1) prepared form 4-chlorophenyl phosphodichloridate and 5-chloro-8-hydroxyquinoline to give 5'-O-dimethoxytrityl-2'-O-tetrahydropyranylnucleoside 3'-(4-chlorophenyl, 5-chloro-8-quinolyl) phosphates (3) in high yields.They are key intermediates for the synthesis of oligoribonucleotides via phosphotriester approach.