76177-10-1

Basic information

• Product Name: N-(2-mercaptoethyl)-2-phenylacetamide
• Synonyms: N-(2-mercaptoethyl)-2-phenylacetamide
• CAS NO: 76177-10-1
• Molecular Weight: 195.285
• Mol File: 76177-10-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: N-(2-mercaptoethyl)-2-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-mercaptoethyl)-2-phenylacetamide(76177-10-1)
• EPA Substance Registry System: N-(2-mercaptoethyl)-2-phenylacetamide(76177-10-1)

Safety Data

• Hazardous Substances Data: 76177-10-1(Hazardous Substances Data)

Upstream product

• 56-17-7 cystamine dihydrochioride 
• 103-80-0 phenylacetyl chloride 
• 156-57-0 2-mercaptoethylamine hydrochloride 
• 140-29-4 phenylacetonitrile 
• 18732-64-4 2-benzyl-4,5-dihydro-thiazole 
• 60-23-1 Cysteamine 
• 103-82-2 phenylacetic acid 
• 91469-94-2 dithiocarbonic acid S-methyl ester S'-(2-methylsulfanylcarbonylamino-ethyl) ester 

Downstream Products

• 92968-99-5 2-Benzylcarbonylamino-1-(2.4-dinitro-phenylmercapto)-aethan 

Relevant articles and documents

Tuning the molecular weight of polymeric amphiphiles as a tool to access micelles with a wide range of enzymatic degradation rates

Enyzme-responsive polymeric assemblies hold great potential for biomedical applications due to the over-expression of disease-associated enzymes, which can be utilized to activate such systems only in afflicted tissues. Herein we demonstrate that the overall molecular weight of polymeric amphiphiles, which have the same hydrophilic/hydrophobic ratio, can be tuned to create polymeric micelles with an extreme range of degradation rates. This approach expands the available set of molecular parameters that can be adjusted to tune the degradation rate of polymeric assemblies, paving new possibilities for rational design of polymeric systems with controlled degradation rates.

Solvent-free tandem synthesis of 2-thiazolines and 2-oxazolines catalyzed by a copper catalyst

Tandem reactions of nitriles with 2-aminoethanethiol hydrochloride or amino alcohols in the presence of a catalytic amount of cupric methacrylate (Cu II2L4, L = methacrylate) were employed to prepare 2-thiazolines and 2-ox

Straightforward microwave-assisted synthesis of 2-thiazolines using Lawesson's reagent under solvent-free conditions

2-Thiazolines are synthesized from carboxylic acids and 1,2-aminoalcohols in the presence of Lawesson's reagent under solventless conditions. The developed method is valid for either substituted or unsubstituted aminoalcohols and a wide variety of aromatic, heteroaromatic and aliphatic carboxylic acids; thus it constitutes a general synthetic method for these kinds of compounds. The role of Lawesson's reagent is dual: to transform the 1,2-aminoalcohol into 1,2-aminothiol and to activate its reaction with the carboxylic acid leading to the formation of a thiazoline ring, all in one pot.