7622-22-2

Basic information

• Product Name: BENZYL (R)-(+)-2-HYDROXY-3-PHENYLPROPIONATE
• Synonyms: BENZYL (R)-(+)-2-HYDROXY-3-PHENYLPROPIONATE;benzyl (R)-(+)2-hydroxy-3-phenylpropionate 97%
• CAS NO: 7622-22-2
• Molecular Formula: C₁₆H₁₆O₃
• Molecular Weight: 256.3
• Product Categories: Chiral Building Blocks;Esters;Organic Building Blocks
• Mol File: 7622-22-2.mol
• Article Data: 15

Chemical Properties

• Melting Point: 20-30 °C(lit.)
• Boiling Point: 228 °C(lit.)
• Flash Point: 113 °C
• Appearance: /
• Density: 1.14 g/mL at 25 °C(lit.)
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: n20/D 1.559(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: BENZYL (R)-(+)-2-HYDROXY-3-PHENYLPROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL (R)-(+)-2-HYDROXY-3-PHENYLPROPIONATE(7622-22-2)
• EPA Substance Registry System: BENZYL (R)-(+)-2-HYDROXY-3-PHENYLPROPIONATE(7622-22-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 7622-22-2(Hazardous Substances Data)

Usage

General Description

Benzyl (R)-(+)-2-hydroxy-3-phenylpropionate, also known as (R)-Benzoin, is a chemical compound commonly used in the fragrance and flavor industry. It is a colorless to pale yellow liquid with a sweet, floral odor. BENZYL (R)-(+)-2-HYDROXY-3-PHENYLPROPIONATE is often used as a fragrance ingredient in perfumes, soaps, and other personal care products. It is also used as a flavoring agent in food products. Additionally, (R)-Benzoin has potential applications in the pharmaceutical industry, particularly in the development of new drugs and medications.

InChI:InChI=1/C16H16O3/c17-15(11-13-7-3-1-4-8-13)16(18)19-12-14-9-5-2-6-10-14/h1-10,15,17H,11-12H2/t15-/m1/s1

Upstream product

• 828-01-3 D-phenyllactic acid 
• 100-39-0 benzyl bromide 
• 93434-59-4 3-Phenyl-2(S)-hydroxypropionic acid benzyl ester 
• 100-51-6 benzyl alcohol 
• 673-06-3 D-(R)-phenylalanine 

Downstream Products

• 111437-25-3 benzyl (R)-(+)-3-phenyl-2-(trifluoromethylsulfonyloxy)propanoate 
• 153052-70-1 benzyl N-Boc-N-methyl-L-leucyl-3-phenyl-D-lactate 
• 212117-43-6 (S)-2-{(R)-3-[(S)-2-(tert-Butoxycarbonyl-methyl-amino)-4-methyl-pentanoyloxy]-2-oxo-azepan-1-yl}-4-methyl-pentanoic acid (R)-1-benzyloxycarbonyl-2-phenyl-ethyl ester 
• 342418-56-8 (R)-1-Phenyl-3-vinyl-pent-4-ene-2,3-diol 
• 188908-75-0 (S)-2-{(R)-3-[(S)-2-(tert-Butoxycarbonyl-methyl-amino)-4-methyl-pentanoyloxy]-2-oxo-pyrrolidin-1-yl}-4-methyl-pentanoic acid (R)-1-benzyloxycarbonyl-2-phenyl-ethyl ester 
• 858972-94-8 2-[2-(tert-butoxycarbonylmethylamino)acetoxy]-3-phenylpropionic acid benzyl ester 
• 903881-52-7 benzyl (S)-2-(3'-bromophenoxy)-3-phenylpropanoate 
• 748789-14-2 (R)-2-(tert-butyldiphenylsilyl)oxy-3-phenylpropanoic acid 
• 903881-65-2 benzyl (S)-2-[3'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]-3-phenylpropanoate 

Relevant articles and documents

Selective Monovalent Galectin-8 Ligands Based on 3-Lactoylgalactoside

Galectin-8 has gained attention as a potential new pharmacological target for the treatment of various diseases, including cancer, inflammation, and disorders associated with bone mass reduction. To that end, new molecular probes are needed in order to better understand its role and its functions. Herein we aimed to improve the affinity and target selectivity of a recently published galectin-8 ligand, 3-O-[1-carboxyethyl]-β-d-galactopyranoside, by introducing modifications at positions 1 and 3 of the galactose. Affinity data measured by fluorescence polarization show that the most potent compound reached a KD of 12 μM. Furthermore, reasonable selectivity versus other galectins was achieved, making the highlighted compound a promising lead for the development of new selective and potent ligands for galectin-8 as molecular probes to examine the protein's role in cell-based and in vivo studies.

ENDOPARASITIC DEPSIPEPTIDES

The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2 are as defined herein. The present invention also contemplates compositions, methods of treatment, and uses as a medicament to treat an animal for an endoparasitic infection with a Formula (1 ) compound.

Organocatalytic synthesis of optically active aryllactic acid derivatives from β-ketosulfoxides

The organocatalytic synthesis of new α-acyloxy-3-arylpropionic thioesters has been accomplished providing some enantioenriched important aryllactic acid derivatives in good yield and enantioselectivities.