858972-94-8

Basic information

• Product Name: Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-, (1R)-2-oxo-2-(phenylmethoxy)-1-(phenylmethyl)ethyl ester
• CAS NO: 858972-94-8
• Molecular Formula: C24H29NO6
• Molecular Weight: 427.497
• Mol File: 858972-94-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-, (1R)-2-oxo-2-(phenylmethoxy)-1-(phenylmethyl)ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-, (1R)-2-oxo-2-(phenylmethoxy)-1-(phenylmethyl)ethyl ester(858972-94-8)
• EPA Substance Registry System: Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-, (1R)-2-oxo-2-(phenylmethoxy)-1-(phenylmethyl)ethyl ester(858972-94-8)

Safety Data

• Hazardous Substances Data: 858972-94-8(Hazardous Substances Data)

Upstream product

• 673-06-3 D-(R)-phenylalanine 
• 828-01-3 D-phenyllactic acid 
• 4530-20-5 BOC-glycine 
• 13734-36-6 N-(tert-butoxycarbonyl)sarcosine 
• 7622-21-1 (R)-benzyl mandelate 

Downstream Products

• 858972-92-6 2-(2-{[2-(2-{2-[(2-tert-butoxycarbonylamino-3-methylpentanoyl)methylamino]acetoxy}-3-phenyl-propionylamino)-3-methylpentanoyl]methylamino}acetoxy)-3-phenylpropionic acid benzyl ester 
• 858972-98-2 (R)-2-(2-{[(2S,3R)-2-((R)-2-{2-[((2S,3R)-2-tert-Butoxycarbonylamino-3-methyl-pentanoyl)-methyl-amino]-acetoxy}-3-phenyl-propionylamino)-3-methyl-pentanoyl]-methyl-amino}-acetoxy)-3-phenyl-propionic acid 

Relevant articles and documents

Total synthesis of hirsutellide A

The total synthesis of hirsutellide A 1 was described. The linear hexadepsipeptide precursor 2 was synthesized in 45% yield from N-Boc-Me-Gly by three coupling reactions with DCC, HATU and BOP-Cl, respectively. Macrocyclization was successfully performed on the fully deprotected amino acid 14 with BOP-Cl in 15% yield and with FDDP in 22% yield.