762233-34-1

Basic information

• Product Name: 1-benzyl 2-methyl (2S,4R)-4-aminopyrrolidine-1,2-dicarboxylate
• Synonyms: (2S,4R)-1-Benzyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate;(2S,4R)-4-amino-1-benzyloxycarbonyl-pyrrolidine-2-carboxylic acid methyl ester
• CAS NO: 762233-34-1
• Molecular Formula: C₁₄H₁₈N₂O₄
• Molecular Weight: 278.30372
• Mol File: 762233-34-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-benzyl 2-methyl (2S,4R)-4-aminopyrrolidine-1,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl 2-methyl (2S,4R)-4-aminopyrrolidine-1,2-dicarboxylate(762233-34-1)
• EPA Substance Registry System: 1-benzyl 2-methyl (2S,4R)-4-aminopyrrolidine-1,2-dicarboxylate(762233-34-1)

Safety Data

• Hazardous Substances Data: 762233-34-1(Hazardous Substances Data)

Usage

General Description

1-benzyl 2-methyl (2S,4R)-4-aminopyrrolidine-1,2-dicarboxylate is a chemical compound with a complex structure and a long name. It is a derivative of the amino acid proline and is commonly used in medicinal chemistry and research. 1-benzyl 2-methyl (2S,4R)-4-aminopyrrolidine-1,2-dicarboxylate has potential applications in the development of pharmaceuticals and drugs due to its structural features and potential biological activities. It may be used as a starting material for the synthesis of various drugs or as a reference compound for analytical purposes. Overall, 1-benzyl 2-methyl (2S,4R)-4-aminopyrrolidine-1,2-dicarboxylate is a versatile chemical that has the potential for various applications in the field of pharmaceuticals and medicinal chemistry.

Upstream product

• 189215-89-2 (2S,4R)-N-1-(benzyloxycarbonyl)-4-azidoproline methyl ester 
• 64187-48-0 methyl (2S,4R)-1-benzyloxycarbonyl-4-hydroxypyrrolidine-2-carboxylate 
• 57653-35-7 (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylic acid 1-benzyl 2-methyl 
• 189215-88-1 1-benzyl 2-methyl (2S,4S)-4-((methylsulfonyl)oxy)pyrrolidine-1,2-dicarboxylate 
• 189215-87-0 (2S,4S)-4-(4-Nitro-benzoyloxy)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 189215-90-5 1-benzyl 2-methyl (2S,4R)-4-(tert-butoxycarbonylamino)pyrrolidine-1,2-dicarboxylate 
• 1035596-36-1 (2S,4R)-1-benzyl 2-methyl 4-(1,3-dioxoisoindolin-2-yl)pyrrolidine-1,2-dicarboxylate 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 189215-90-5 1-benzyl 2-methyl (2S,4R)-4-(tert-butoxycarbonylamino)pyrrolidine-1,2-dicarboxylate 
• 489453-06-7 (2S,4R)-4-[((2S,4R)-1-Benzyloxycarbonyl-4-tert-butoxycarbonylamino-pyrrolidine-2-carbonyl)-amino]-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 489453-07-8 (2S,4R)-4-({(2S,4R)-1-Benzyloxycarbonyl-4-[((2S,4R)-1-benzyloxycarbonyl-4-tert-butoxycarbonylamino-pyrrolidine-2-carbonyl)-amino]-pyrrolidine-2-carbonyl}-amino)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 803706-19-6 (2S,4R)-4-({(2S,4R)-1-Benzyloxycarbonyl-4-[((2S,4R)-1-benzyloxycarbonyl-4-tert-butoxycarbonylamino-pyrrolidine-2-carbonyl)-amino]-pyrrolidine-2-carbonyl}-amino)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 
• 473806-21-2 4-tertbutyloxycarbonylamino-L-trans-proline methyl ester 
• 189215-92-7 (2S,4R)-1-[2-(4-Benzyloxycarbonylamino-2-oxo-2H-pyrimidin-1-yl)-acetyl]-4-tert-butoxycarbonylamino-pyrrolidine-2-carboxylic acid methyl ester 
• 1035596-37-2 (2S,4R)-1-benzyl 2-methyl 4-benzamidopyrrolidine-1,2-dicarboxylate 
• 1163706-99-7 (2S,4R)-4-dimethylamino-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 

Relevant articles and documents

Dihydropyridine compound and application thereof to drugs

The invention relates to a dihydropyridine compound and application of the dihydropyridine compound serving as a drug, in particular to application of the dihydropyridine compound serving as a drug for treating and preventing hepatitis B. Specifically, the invention relates to the compound shown as the general formula (I) or (Ia) (please see the specifications for the general formula (I) or (Ia))or stereoisomers, tautomer, a nitrogen oxide, solvate, metabolites and medically acceptable salt of the compound or a prodrug of the compound, wherein all variables are defined in the specification. The invention further relates to application of the compound shown as the general formula (I) or (Ia) or enantiomers, non-enantiomers, the tautomer, hydrates, the solvate or the medically acceptable salt of the compound serving as drugs, in particular to application of the compound or the enantiomers, the non-enantiomers, the tautomer, the hydrates, the solvate or the medically acceptable salt of the compound serving as the drugs for treating and preventing hepatitis B.

Synthesis of new building blocks for peptide nucleic acids containing monomers with variations in the backbone

New PNA monomers containing aminoprolines or pyrrolidines as backbones have been synthesized. Oligomerisation was carried out on a solid support. Resistance to enzymatic degradation was tested.