76434-54-3Relevant articles and documents
Antibacterial agent as well as synthetic method and application thereof
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Paragraph 0046; 0048; 0049; 0056; 0063, (2017/10/07)
The invention relates to an antibacterial agent as well as a synthetic method and application thereof and belongs to the field of biotechnology. The antibacterial agent is 3,3',4',5,5'-pentahydroxyflavanone. The synthetic method comprises the following st
Identification and initial SAR of silybin: An Hsp90 inhibitor
Zhao, Huiping,Brandt, Gary E.,Galam, Lakshmi,Matts, Robert L.,Blagg, Brian S.J.
scheme or table, p. 2659 - 2664 (2011/06/22)
Through Hsp90-dependent firefly luciferase refolding and Hsp90-dependent heme-regulated eIF2α kinase (HRI) activation assays, silybin was identified as a novel Hsp90 inhibitor. Subsequently, a library of silybin analogues was designed, synthesized and evaluated. Initial SAR studies identified the essential, non-essential and detrimental functionalities on silybin that contribute to Hsp90 inhibition.
Heterocycles. XVII. Sodium borohydride reduction of flavanonols and hydrolysis of (±)-fistacacidin acetates
Takahashi,Kubota,Iguchi,Onda
, p. 3134 - 3141 (2007/10/02)
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