76470-01-4

Basic information

• Product Name: methyl 2-(2-oxocyclohexyl)-1-pyrrolidinecarboxylate
• Synonyms: methyl 2-(2-oxocyclohexyl)-1-pyrrolidinecarboxylate
• CAS NO: 76470-01-4
• Molecular Weight: 225.288
• Mol File: 76470-01-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 2-(2-oxocyclohexyl)-1-pyrrolidinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(2-oxocyclohexyl)-1-pyrrolidinecarboxylate(76470-01-4)
• EPA Substance Registry System: methyl 2-(2-oxocyclohexyl)-1-pyrrolidinecarboxylate(76470-01-4)

Safety Data

• Hazardous Substances Data: 76470-01-4(Hazardous Substances Data)

Upstream product

• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 56475-88-8 methyl 2-methoxypyrrolidine-1-carboxylate 
• 56475-80-0 N-(methoxycarbonyl)pyrrolidine 
• 74761-41-4 (S)-1-(methoxycarbonyl)pyrrolidine-2-carboxylic acid 
• 670-80-4 4-cyclohexen-1-ylmorpholine 

Relevant articles and documents

Asymmetric introduction of nucleophiles to the 2-position of pyrrolidine ring through N-acylpyrrolidinium ion

Asymmetric carbon-carbon bond-forming reaction at the 2-position of a pyrrolidine ring was achieved. The reaction involved a chiral Ti(IV) catalyzed coupling between 1-methoxycarboyl-2-methoxypyrrolidine and silyl enol ethers to afford 2-substituted pyrro

Direct oxidative carbon-carbon bond formation using the cation pool method. 1. Generation of iminium cation pools and their reaction with carbon nucleophiles

We have developed a method that involves the generation of a cation pool using low-temperature electrolysis, and then its reaction with nucleophiles under non-oxidative conditions. This one-pot method solves problems associated with conventional oxidative generation of cations and their in situ reaction with nucleophiles, and provides an efficient method for direct oxidative carbon-carbon bond formation. As an example of this method, generation of cation pools from carbamates by low-temperature electrolysis (-72°C) and their reactions with carbon nucleophiles such as allylsilanes, enol silyl ethers, and enol acetates were examined and the desired products were obtained in good yields. Aromatic compounds and 1,3-dicarbonyl compounds can also be utilized as carbon nucleophiles. The present method was also applied to combinatorial parallel synthesis using a robotic synthesizer.