768392-48-9

Basic information

• Product Name: Benzene, [(1R)-1-ethyl-1-methyl-2-propenyl]-
• CAS NO: 768392-48-9
• Molecular Formula: C12H16
• Molecular Weight: 160.259
• Mol File: 768392-48-9.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Benzene, [(1R)-1-ethyl-1-methyl-2-propenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(1R)-1-ethyl-1-methyl-2-propenyl]-(768392-48-9)
• EPA Substance Registry System: Benzene, [(1R)-1-ethyl-1-methyl-2-propenyl]-(768392-48-9)

Safety Data

• Hazardous Substances Data: 768392-48-9(Hazardous Substances Data)

Upstream product

• 74-85-1 ethene 
• 2039-93-2 1-ethylstyrene 
• 54976-38-4 (E)-3-phenylbut-2-en-1-ol 
• 54976-39-5 (E)-1-bromo-3-phenyl-2-butene 
• 925-90-6 ethylmagnesium bromide 
• 93-55-0 1-phenyl-propan-1-one 
• 98-86-2 acetophenone 
• 6051-52-1 2-phenylbut-3-en-2-ol 
• 54976-37-3 (Z)-3-phenyl-2-buten-1-ol 
• 945-93-7 ethyl (Z)-3-phenylbut-2-enoate 
• 54976-39-5 (Z)-(4-bromobut-2-en-2-yl)benzene 
• 811-49-4 ethyllithium 
• 39171-59-0 (4-bromobut-2-en-2-yl)benzene 
• 1794-51-0 1-chloro-3-phenyl-2-butene 

Downstream Products

• 3968-68-1 (+)-(2S)-2-Methyl-2-phenylbutanoic acid 

Relevant articles and documents

All-carbon quaternary centers via catalytic asymmetric hydrovinylation. New approaches to the exocyclic side chain stereochemistry problem

1-Alkylstyrenes undergo efficient hydrovinylation (coupling with ethylene) in the presence of 1 mol % of a Ni catalyst prepared from [(allyl)NiBr]2, Na+BAr4- (Ar = 3,5-bistrifluoromethylphenyl), and phosphoramid

P-Chiral Monophosphorus Ligands for Asymmetric Copper-Catalyzed Allylic Alkylation

Asymmetric copper-catalyzed allylic alkylation between allyl bromides and alkyl Grignard reagents using a P-chiral monophosphorus ligand is described. A range of terminal olefins bearing tertiary or quaternary carbon centers were formed in good branched/linear selectivities and excellent enantioselectivities at copper loadings as low as 0.5 mol %.

Low-Pressure Cobalt-Catalyzed Enantioselective Hydrovinylation of Vinylarenes

An efficient and practical protocol for the enantioselective cobalt-catalyzed hydrovinylation of vinylarenes with ethylene at low (1.2 bar) pressure has been developed. As precatalysts, stable [L2CoCl2] complexes are employed that are activated in situ with Et2AlCl. A modular chiral TADDOL-derived phosphine-phosphite ligand was identified that allows the conversion of a broad spectrum of substrates, including heterocyclic vinylarenes and vinylferrocene, to smoothly afford the branched products with up to 99 % ee and virtually complete regioselectivity. Even polar functional groups, such as OH, NH2, CN, and CO2R, are tolerated.

Enantioselective synthesis of all-carbon quaternary stereogenic centers via copper-catalyzed asymmetric allylic alkylation of (Z)-allyl bromides with organolithium reagents

A copper/phosphoramidite catalyzed asymmetric allylic alkylation of Z trisubstituted allyl bromides with organolithium reagents is reported. The reaction affords all-carbon quaternary stereogenic centers in high yields and very good regio- and enantiosele