7697-29-2 Usage
Description
4-Chloro-3-methylbenzoic acid, a white to light yellow crystal powder, is an organic compound with the molecular formula C8H7ClO2. It is characterized by the presence of a chlorine atom at the 4th position and a methyl group at the 3rd position on the benzene ring, with a carboxylic acid functional group. 4-Chloro-3-methylbenzoic acid is known for its chemical stability and reactivity, making it a versatile building block in the synthesis of various pharmaceuticals and chemicals.
Uses
Used in Pharmaceutical Industry:
4-Chloro-3-methylbenzoic acid is used as a reactant for the preparation of tipifarnib analogs, which are cancer drugs specifically designed to target Chagas disease. These analogs are developed to inhibit the farnesyltransferase enzyme, which plays a crucial role in the growth and survival of the Trypanosoma cruzi parasite responsible for Chagas disease. By incorporating 4-chloro-3-methylbenzoic acid into the structure of these analogs, researchers aim to enhance their efficacy and selectivity against the disease.
Used in Chemical Synthesis:
Due to its unique chemical structure, 4-chloro-3-methylbenzoic acid can be employed as a building block in the synthesis of various organic compounds, such as dyes, pigments, and other specialty chemicals. Its reactivity with different functional groups allows for the creation of a wide range of products with diverse applications in various industries.
Used in Research and Development:
4-Chloro-3-methylbenzoic acid is also utilized in research and development for the study of its chemical properties, reactivity, and potential applications in various fields. Researchers can use this compound to explore new synthetic routes, develop novel compounds, and investigate its potential as a precursor for other valuable chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 7697-29-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,9 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7697-29:
(6*7)+(5*6)+(4*9)+(3*7)+(2*2)+(1*9)=142
142 % 10 = 2
So 7697-29-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H7ClO2/c1-5-4-6(8(10)11)2-3-7(5)9/h2-4H,1H3,(H,10,11)
7697-29-2Relevant articles and documents
INHIBITORS OF STEAROYL-COA DESATURASE
-
, (2009/06/27)
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity.
Photolyis of 2-Nitrodiphenylmethanes in Isopropanol and Acidified Aqueous Ethanol
Christudhas, M.,Jacob, E. Dominic,Joshua, C. P.
, p. 815 - 817 (2007/10/02)
2-Nitrodiphenylmethane (1a) on irradiation in isopropanol and acidified ethanol yields benzoic acids as the major product. 3-Phenyl-2,1-benzisoxazole (2a) and acridone (3a) are also formed, though in lower yields. 4,4'-Dichloro/bromo-5,5'-dimethyl-2-nitrodiphenylmethanes (1b, c) on similar irradiation yields 4-halo-3-methylbezoic acid (4) as the major product. 5-Methyl-4-halo-3-(4'-halo-3'-methylphenyl)-2,1-benzisoxazole (2b, c) and acridones (3b, c) are also formed.A plausible mechanism for the formation of various products in the photoreactions is discussed.
