19482-16-7

Basic information

• Product Name: 4,4'-dichloro-3,3'-dimethyl-1,1'-biphenyl
• Synonyms: 4,4'-dichloro-3,3'-dimethyl-1,1'-biphenyl
• CAS NO: 19482-16-7
• Molecular Weight: 251.155
• Mol File: 19482-16-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,4'-dichloro-3,3'-dimethyl-1,1'-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-dichloro-3,3'-dimethyl-1,1'-biphenyl(19482-16-7)
• EPA Substance Registry System: 4,4'-dichloro-3,3'-dimethyl-1,1'-biphenyl(19482-16-7)

Safety Data

• Hazardous Substances Data: 19482-16-7(Hazardous Substances Data)

Upstream product

• 5422-50-4 1-bromo-(2-methylphenoxymethyl)benzene 
• 161950-10-3 4-chloro-3-methylbenzeneboronic acid 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 99-90-1 para-bromoacetophenone 

Downstream Products

• 7697-29-2 4-chloro-3-methylbenzoic acid 

Relevant articles and documents

Polymer-Assisted Solution-Phase (PASP) Suzuki Couplings Employing an Anthracene-Tagged Palladium Catalyst

A general method for polymer-assisted solution-phase (PASP) Suzuki reactions employing a combination of anthracene-tagged palladium catalyst and anthracene-tagged boronic acid with a polymer-supported carbonate base is reported. The anthracene-tagged catalyst allows for the easy removal of the Pd catalyst along with the dissociated phosphine ligand and phosphine oxide byproducts by sequestration through a chemoselective Diels-Alder reaction with a maleimide resin. The polymer-supported carbonate base facilitates the removal of excess boronic acid and the borane-containing byproducts present at the end of the coupling reaction. The Suzuki coupling reaction can be efficiently conducted by using combinations of the anthracene-tagged Pd catalyst, polymer-supported carbonate base, and anthracene-tagged boronic acid to yield the desired product in high purity and yield without the use of chromatography.