77266-69-4

Basic information

• Product Name: Benzoic acid, 4-(2-aMinoethyl)-, ethyl ester
• Synonyms: Benzoic acid, 4-(2-aMinoethyl)-, ethyl ester;Ethyl 4-(2-aMinoethyl)benzoate;RBLUWLZGAZETKS-UHFFFAOYSA-N
• CAS NO: 77266-69-4
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.2423
• Mol File: 77266-69-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 4-(2-aMinoethyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(2-aMinoethyl)-, ethyl ester(77266-69-4)
• EPA Substance Registry System: Benzoic acid, 4-(2-aMinoethyl)-, ethyl ester(77266-69-4)

Safety Data

• Hazardous Substances Data: 77266-69-4(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 1199-69-5 4-(2-aminoethyl)benzoic acid 
• 52062-92-7 4-(2-bromoethyl)benzoic acid 
• 74003-31-9 4-bromoethylbenzoic acid ethyl ester 
• 72054-56-9 4-(2-bromoethyl)benzonitrile 
• 524743-24-6 ethyl 4-(2-phthalimidoethyl)benzoate 
• 60531-36-4 4-(2-amino-ethyl)-benzoic acid hydrochloride 
• 26496-94-6 Ethyl 4-(bromomethyl)benzoate 
• 83901-88-6 4-cyanomethylbenzoic acid ethyl ester 

Downstream Products

• 65779-39-7 4-[2-(2-10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl-acetylamino)-ethyl]-benzoic acid ethyl ester 
• 65779-35-3 ethyl 4-[2-(fluorene-9-carboxamido)-ethyl]-benzoate 
• 65779-43-3 4-[2-(2-9,10-Dihydro-anthracen-9-yl-acetylamino)-ethyl]-benzoic acid ethyl ester 
• 69732-19-0 4-[2-(2-9H-Fluoren-9-yl-propionylamino)-ethyl]-benzoic acid ethyl ester 
• 60531-31-9 4-(2-<2-ethoxy-5-chloro-benzamido>-ethyl)-benzoic acid ethyl ester 
• 65779-41-1 4-{2-[2-(2,6-Dimethyl-9H-fluoren-9-yl)-acetylamino]-ethyl}-benzoic acid ethyl ester 
• 77266-17-2 ethyl 4-(2-(5-chloro-2-heptamethyleneimino-benzoylamino)-ethyl)-benzoate 
• 78252-68-3 ethyl 4-(2-(5-chloro-2-heptamethyleneimino-benzoylamino)-ethyl)-benzoate 
• 78252-70-7 ethyl 4-(2-(5-chloro-2-nonanmethyleneimino-benzoylamino)-ethyl)-benzoate 
• 78252-72-9 ethyl 4-(2-(5-chloro-2-decamethyleneimino-benzoylamino)-ethyl)-benzoate 
• 493036-25-2 4-[2-((S)-5-Benzyloxy-4-hydroxy-pentanoylamino)-ethyl]-benzoic acid ethyl ester 
• 493036-27-4 (R)-N'-[2-(4-carboethoxyphenyl)ethyl]-5-hydroxymethyl-2-pyrrolidinone 
• 493036-26-3 (R)-N'-[2-(4-carboethoxyphenyl)ethyl]-5-benzyloxymethyl-2-pyrrolidinone 
• 819067-23-7 4-{2-[(R)-2-Oxo-5-((E)-3-oxo-oct-1-enyl)-pyrrolidin-1-yl]-ethyl}-benzoic acid ethyl ester 

Relevant articles and documents

Overcoming inaccessibility of fluorinated imines-synthesis of functionalized amines from readily available fluoroacetamides

Although imines are convenient substrates for the synthesis of functionalized amines, they may be hard to obtain, as in the case of fluorinated imines. To aid in overcoming this issue, we propose a protocol of corresponding amine synthesis from simple fluoroacetic acid-derived amides using Schwartz's reagent.

MTH1 INHIBITORS FOR TREATMENT OF INFLAMMATORY AND AUTOIMMUNE CONDITIONS

A compound of formula (I), or a pharmaceutically acceptable salt thereof, for use in the treatment of autoimmune diseases and inflammatory conditions.

Lactams as EP4 prostanoid receptor agonists. 3. Discovery of N-ethylbenzoic acid 2-pyrrolidinones as subtype selective agents

Two distinct synthetic schemes were applied to access heteroatom-containing α-chain lactams or lactams terminated as aryl acids. The latter lactams were devised using a pharmacophore for EP4 receptor activity. γ-Lactams were characterized for their prostanoid EP receptor affinities and EP 4 activity and found to be selective for the EP2 and EP4 receptors or selective for the EP4 subtype. Benzoic acid 17 displayed enhanced in vivo exposure relative to 3.