77281-39-1

Basic information

• Product Name: 3-nitrophenyl β-chloroethyl sulphone
• Synonyms: 3-nitrophenyl β-chloroethyl sulphone
• CAS NO: 77281-39-1
• Molecular Weight: 249.675
• Mol File: 77281-39-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-nitrophenyl β-chloroethyl sulphone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-nitrophenyl β-chloroethyl sulphone(77281-39-1)
• EPA Substance Registry System: 3-nitrophenyl β-chloroethyl sulphone(77281-39-1)

Safety Data

• Hazardous Substances Data: 77281-39-1(Hazardous Substances Data)

Upstream product

• 938-09-0 2-chloroethyl phenyl sulfone 
• 20611-21-6 2-(phenylsulfonyl)ethanol 

Downstream Products

• 20171-20-4 3-(2-chloro-ethanesulfonyl)-aniline 
• 78735-19-0 (3-nitrophenyl)vinylsulfone 

Relevant articles and documents

KINETICS AND MECHANISM OF THE INTERACTION OF AMINES WITH ARYL β-HALOETHYL SULPHONES

The influence of a number of factors, i.e. amine basicity, substrate structure, temperature and deuterium isotope effect, on the rate of phenyl β-bromoethyl sulphone and aryl β-chloroethyl sulphone 1,2-elimination by reaction with amines in acetonitrile was investigated.On the basis of a comparative analysis of the ρ0, β, kH/kD, ΔH(excit.) and ΔS25(excit.) values obtained with those for the reaction of β-halopropiophenone 1,2-elimination, the conclusion was drawn that the E2 mechanism with an anion-like transition state occurs for the given substrates under the conditions studied.