78735-19-0

Basic information

• Product Name: Benzene, 1-(ethenylsulfonyl)-3-nitro-
• CAS NO: 78735-19-0
• Molecular Formula: C8H7NO4S
• Molecular Weight: 213.214
• Mol File: 78735-19-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(ethenylsulfonyl)-3-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(ethenylsulfonyl)-3-nitro-(78735-19-0)
• EPA Substance Registry System: Benzene, 1-(ethenylsulfonyl)-3-nitro-(78735-19-0)

Safety Data

• Hazardous Substances Data: 78735-19-0(Hazardous Substances Data)

Upstream product

• 1202639-05-1 C₂₁H₂₃N₅O₁₂S 
• 77281-39-1 3-nitrophenyl β-chloroethyl sulphone 

Downstream Products

• 931-59-9 benzenesulfenyl chloride 
• 91819-25-9 1-ethoxy-2-(3-nitro-benzenesulfonyl)-ethane 
• 91004-92-1 1-methoxy-2-(3-nitro-benzenesulfonyl)-ethane 
• 93136-98-2 1-butoxy-2-(3-nitro-benzenesulfonyl)-ethane 

Relevant articles and documents

CONTROLLED DRUG RELEASE FROM SOLID SUPPORTS

The invention relates to solid supports useful in medical applications that provide controlled release of drugs, such as peptides, nucleic acids and small molecules. The drugs are covalently coupled to the solid support through a linkage that releases the drug or a prodrug through controlled beta elimination.

KINETICS AND MECHANISM OF THE INTERACTION OF AMINES WITH ARYL β-HALOETHYL SULPHONES

The influence of a number of factors, i.e. amine basicity, substrate structure, temperature and deuterium isotope effect, on the rate of phenyl β-bromoethyl sulphone and aryl β-chloroethyl sulphone 1,2-elimination by reaction with amines in acetonitrile was investigated.On the basis of a comparative analysis of the ρ0, β, kH/kD, ΔH(excit.) and ΔS25(excit.) values obtained with those for the reaction of β-halopropiophenone 1,2-elimination, the conclusion was drawn that the E2 mechanism with an anion-like transition state occurs for the given substrates under the conditions studied.