77311-68-3

Basic information

• Product Name: Benzenemethanol, 3-hydroxy-4-(1-methylethyl)-
• CAS NO: 77311-68-3
• Molecular Formula: C10H14O2
• Molecular Weight: 166.22
• Mol File: 77311-68-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 3-hydroxy-4-(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 3-hydroxy-4-(1-methylethyl)-(77311-68-3)
• EPA Substance Registry System: Benzenemethanol, 3-hydroxy-4-(1-methylethyl)-(77311-68-3)

Safety Data

• Hazardous Substances Data: 77311-68-3(Hazardous Substances Data)

Usage

Properties

1. Chemical name: Benzenemethanol, 3-hydroxy-4-(1-methylethyl)-
2. Common name: 4-(1-Methylethyl)-3-hydroxybenzyl alcohol
3. Chemical class: Phenols and phenolic derivatives
4. Physical state: Colorless liquid
5. Odor: Fragrant with a floral and honey-like smell

Uses

1. Production of perfumes and fragrances
2. Manufacturing of pharmaceuticals
3. Dyes production
4. Flavoring agent in the food industry

Additional properties

1. Potential antioxidant properties
2. Potential antibacterial properties
3. Compounds of interest in medicine, cosmetics, and food science

Upstream product

• 19420-59-8 3-hydroxy-4-isopropyl-benzoic acid 
• 77311-67-2 3-Acetoxy-4-isopropylbenzoic acid 
• 53878-05-0 7-bromomethyl-4-methylcoumarin 
• 71745-51-2 3-Hydroxy-4-isopropylbenzoesaeuremethylester 
• 528-79-0 2-isopropyl-5-methylphenyl acetate 
• 77878-31-0 7-acetoxymethyl-4-methylcoumarin 
• 59555-33-8 3-acetoxy-4-isopropyl-benzyl acetate 

Downstream Products

• 66498-33-7 4-isopropyl-3-methoxy-benzyl alcohol 
• 22518-01-0 3-hydroxy-4-isopropylbenzyl alcohol diisobutyrate 
• 33280-66-9 3-Methyl-butyric acid 4-isopropyl-3-methoxy-benzyl ester 
• 33280-65-8 4-isopropyl-3-methoxy-benzyl isobutyrate 
• 114649-69-3 Acetic acid 5-chloromethyl-2-isopropyl-phenyl ester 
• 114649-71-7 3-hydroxy-4-isopropylbenzyl cyanide 
• 91970-76-2 3-hydroxy-4-isopropylphenylacetic acid 
• 59555-33-8 3-acetoxy-4-isopropyl-benzyl acetate 
• 114649-68-2 3-(acetoxy)-4-(1-methylethyl)-benzenemethanol 
• 114649-70-6 5-Iodomethyl-2-isopropyl-phenol 

Relevant articles and documents

Oxidation of Acetoxy-(alkyl)-arenes and Alkoxy-(alkyl)-arenes with Benzyltriethylammonium Permanganate; Convenient Syntheses of Some Natural Products

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Synthesis of Two Naturally Occuring Oxygenated Oxiranes Related to Thymol

7-Acetoxymethyl-4-methylcoumarin (3) on heating with aq.NaOH furnishes 2-(2'-hydroxy-4'-hydroxymethylphenyl)propene (5), which has been transformed in two steps to the naturally occuring oxirane, 2-methyl-2-(2'-hydroxy-4'-hydroxymethylphenyl)oxirane diisobutyrate (14).Selenium dioxide oxidation of 2-(2'-acetoxy-4'-acetoxymethylphenyl)propene (7) yields 2-(2'-acetoxy-4'-acetoxymethylphenyl)prop-2-en-1-al (8) which on reduction with NaBH4 and subsequent saponification furnishes 2-(2'-hydroxy-4'-hydroxymethylphenyl)prop-2-en-1-ol (9).The triol (9) has been transformed in two steps into 2-hydroxymethyl-2-(2'-hydroxy-4'-hydroxymethylphenyl)oxirane triisobutyrate (15).An alternative synthesis of 9 is also described.The preparation of o-isopropenylphenol (5) by the action of aq.NaOH alone, instead of NaOH-ethylene glycol, on the coumarin (3) is significant.This modification provides a conveniant route for the preparation of o-isopropenylphenols in those cases where the use of NaOH-ethylene glycol is not satisfactory.