774-40-3Relevant articles and documents
Tunable System for Electrochemical Reduction of Ketones and Phthalimides
Chen, Gong,Qiao, Tianjiao,Wang, Yaxin,Zhang, Jian,Zhao, Jianyou
supporting information, p. 3297 - 3302 (2021/10/14)
Herein, we report an efficient, tunable system for electrochemical reduction of ketones and phthalimides at room temperature without the need for stoichiometric external reductants. By utilizing NaN3 as the electrolyte and graphite felt as both the cathode and the anode, we were able to selectively reduce the carbonyl groups of the substrates to alcohols, pinacols, or methylene groups by judiciously choosing the solvent and an acidic additive. The reaction conditions were compatible with a diverse array of functional groups, and phthalimides could undergo one-pot reductive cyclization to afford products with indolizidine scaffolds. Mechanistic studies showed that the reactions involved electron, proton, and hydrogen atom transfers. Importantly, an N3/HN3 cycle operated as a hydrogen atom shuttle, which was critical for reduction of the carbonyl groups to methylene groups.
Strongly enhanced acidity and activity of amorphous silica–alumina by formation of pentacoordinated AlV species
Wang, Zichun,Jiang, Yijiao,Jin, Fangzhu,Stampfl, Catherine,Hunger, Michael,Baiker, Alfons,Huang, Jun
, p. 1 - 7 (2019/02/27)
Tailoring high-performance aluminosilicates plays a key role in the efficient and clean production of high-value chemicals. Recent work reveals that pentacoordinated Al (AlV) species can significantly enhance the Br?nsted acidity of amorphous silica–alumina (ASA), compared with that typically dominated by tetracoordinated Al species. However, the controlled synthesis of AlV-rich ASAs is challenging. Employing xylene as the solvent in a flame-spray pyrolysis process, we synthesized AlV-rich ASAs successfully. The high combustion enthalpy of xylene (36.9 kJ/ml) results in a high flame temperature, promoting the formation and distribution of metastable AlV species in the silica network forming Br?nsted acid sites. This provides a promising route for the controlled synthesis of AlV-rich ASAs with higher Br?nsted acidity. As an example, AlV-rich ASAs are shown to exhibit superior catalytic performance in phenylglyoxal conversion to ethyl mandelate in ethanol compared with that achieved with other acid catalysts, attaining an ethyl mandelate yield of 99.8%.
Cobalt-Catalyzed Transfer Hydrogenation of α-Ketoesters and N-Cyclicsulfonylimides Using H2O as Hydrogen Source
Gao, Yang,Zhang, Xuexin,Laishram, Ronibala Devi,Chen, Jingchao,Li, Kangkui,Zhang, Keyang,Zeng, Guangzhi,Fan, Baomin
supporting information, p. 3991 - 3997 (2019/08/02)
A Co-catalyzed effective transfer hydrogenation of various α-ketoesters and N-cyclicsulfonylimides by safe and environmentally benign H2O as hydrogen source is described. The reaction used easily available and easy to handle zinc metal as a reductant. Interestingly, the catalytic system does not require ligand for reduction of N-cyclicsulfonylimides. (Figure presented.).