774213-79-5Relevant articles and documents
Allosteric N-acetamide-indole-6-carboxylic acid thumb pocket 1 inhibitors of hepatitis C virus NS5B polymerase-Acylsulfonamides and acylsulfamides as carboxylic acid replacements
Beaulieu, Pierre L.,Coulombe, Rene,Gillard, James,Brochu, Christian,Duan, Jianmin,Garneau, Michel,Jolicoeur, Eric,Kuhn, Peter,Poupart, Marc-Andre,Rancourt, Jean,Stammers, Timothy A.,Thavonekham, Bounkham,Kukolj, George
, p. 66 - 81 (2013/03/14)
Acylsulfonamide and acylsulfamide as surrogates for the carboxylic acid function of N-acetamide-indole-6-carboxylic acids were evaluated as allosteric inhibitors of hepatitis C virus (HCV) NS5B polymerase. Several analogs displayed excellent antiviral pot
AROMATIC HETEROCYCLIC FUSED INDOLOBENZADIAZEPINE HCV NS5B INHIBITORS
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Page/Page column 25-26, (2009/10/22)
The disclosure provides compounds of formula (I), including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
TETRACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS
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Page/Page column 20, (2008/06/13)
The present invention relates to tetracyclic indole derivatives of formula (I): wherein Ar, A, R1, R2, L, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, a