77422-39-0

Basic information

• Product Name: N-benzyloxycarbonyl-S-(diphenyl-4-pyridylmethyl)-L-cysteine 2,4,5-trichlorophenyl ester
• Synonyms: N-benzyloxycarbonyl-S-(diphenyl-4-pyridylmethyl)-L-cysteine 2,4,5-trichlorophenyl ester
• CAS NO: 77422-39-0
• Molecular Weight: 678.035
• Mol File: 77422-39-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyloxycarbonyl-S-(diphenyl-4-pyridylmethyl)-L-cysteine 2,4,5-trichlorophenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyloxycarbonyl-S-(diphenyl-4-pyridylmethyl)-L-cysteine 2,4,5-trichlorophenyl ester(77422-39-0)
• EPA Substance Registry System: N-benzyloxycarbonyl-S-(diphenyl-4-pyridylmethyl)-L-cysteine 2,4,5-trichlorophenyl ester(77422-39-0)

Safety Data

• Hazardous Substances Data: 77422-39-0(Hazardous Substances Data)

Upstream product

• 62982-15-4 N-benzyloxycarbonyl-S-(diphenyl-4-pyridylmethyl)-L-cysteine 
• 95-95-4 2,4,5-trichlorophenol 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 1620-30-0 diphenyl(pyridin-4-yl)methanol 
• 14548-46-0 4-Benzoylpyridine 
• 62982-12-1 S-(diphenyl-4-pyridylmethyl)-L-cysteine 
• 62982-14-3 N-t-butoxycarbonyl-S-(diphenyl-4-pyridylmethyl)-L-cysteine dicyclohexylammonium salt 

Relevant articles and documents

Amino-acids and Peptides. Part 45. The Protection of the Thiol Function of Cysteine and the Imidazole-N of Histidine by the Diphenyl-4-pyridylmethyl Group

S-(Diphenyl-4-pyridylmethyl)-L-cysteine (1) and its derivatives (2)-(7) have been prepared and used in peptide synthesis.In contrast to the analogous S-trityl group, this protection is stable in acid but it is cleaved readily by zinc-acetic acid, by mercury(II) acetate, by iodine, and by electrolytic reduction.N(Im)-Diphenyl-4-pyridylmethyl-L-histidine derivatives (9)-(13) are also reported; the protecting group is again stable to acid but cleaved by hydrogenolysis, by zinc-acetic acid, and by electrolytic reduction, and it has been used in the synthesis of L-histidyl-L-leucine, -L-phenylalanine, and -glycine.