775-31-5

Basic information

• Product Name: 1-(4-FLUOROPHENYL)-2-NITROPROPENE
• Synonyms: 1-fluoro-4-(2-nitropropenyl)-benzen;1-Fluoro-4-[(1E)-2-nitro-1-propenyl]benzene;Benzene, 1-fluoro-4-(2-nitropropenyl)-;p-Fluoro-beta-nitropropenylbenzene;4'-FLUORO-BETA-METHYL-BETA-NITROSTYRENE;1-FLUORO-4-(2-NITROPROP-1-ENYL)BENZENE;1-(4-FLUOROPHENYL)-2-NITROPROP-1-ENE;1-(4-FLUOROPHENYL)-2-NITROPROPENE
• CAS NO: 775-31-5
• Molecular Formula: C9H8FNO2
• Molecular Weight: 181.16
• Product Categories: Propanes/propenes
• Mol File: 775-31-5.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 262.2°C at 760 mmHg
• Flash Point: 112.4°C
• Appearance: /
• Density: 1.23g/cm³
• Vapor Pressure: 0.018mmHg at 25°C
• Refractive Index: 1.565
• CAS DataBase Reference: 1-(4-FLUOROPHENYL)-2-NITROPROPENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-FLUOROPHENYL)-2-NITROPROPENE(775-31-5)
• EPA Substance Registry System: 1-(4-FLUOROPHENYL)-2-NITROPROPENE(775-31-5)

Safety Data

• Hazardous Substances Data: 775-31-5(Hazardous Substances Data)

Usage

General Description

1-(4-Fluorophenyl)-2-nitropropene is a chemical compound with the molecular formula C9H8FNO2. It is a nitroalkene, which means it contains a nitro group attached to an alkene double bond. 1-(4-FLUOROPHENYL)-2-NITROPROPENE is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is known for its potential use in the production of organic compounds and is often utilized in research and development of new materials and products. However, it is important to handle this chemical with care, as it may pose potential hazards if not handled properly.

InChI:InChI=1/C9H8FNO2/c1-7(11(12)13)6-8-2-4-9(10)5-3-8/h2-6H,1H3/b7-6+

Upstream product

• 79-24-3 Nitroethane 
• 459-57-4 4-fluorobenzaldehyde 
• 135711-46-5 Butyl-[1-(4-fluoro-phenyl)-2-nitro-propyl]-amine 
• 459-56-3 4-fluorobenzylic alcohol 
• 222025-82-3 1-(4-Fluoro-phenyl)-2-nitro-propan-1-ol 
• 593-51-1 methylamine hydrochloride 
• 140-75-0 para-fluorobenzylamine 

Downstream Products

• 124401-41-8 1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrole-3-carboxanilide 
• 122223-62-5 4-(4-fluorophenyl)-2-isopropyl-N,1-diphenyl-1H-pyrrole-3-carboxamide 
• 122223-49-8 1-phenyl-2-isopropyl-4-(4-fluorophenyl)-5-methyl-1H-pyrrole-3-carboxanilide 
• 124401-42-9 1-cyclohexyl-2-isopropyl-4-(4-fluorophenyl)-1H-pyrrole-3-carboxanilide 
• 459-02-9 4-fluoroamphetamine 
• 222026-14-4 3-(4-fluoro-phenyl)-4-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester 
• 222026-58-6 3-(4-fluoro-phenyl)-1,4-dimethyl-1H-pyrrole-2-carboxylic acid tert-butyl ester 
• 222026-60-0 1-allyl-3-(4-fluoro-phenyl)-4-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester 
• 222026-62-2 1-benzyl-3-(4-fluoro-phenyl)-4-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester 
• 103596-36-7 (R,S)-(+/-)-α-methyl-β-(4-fluorophenyl)-N-propynylethylamine 
• 103596-43-6 N-methyl-N-(1-(4-fluoro-phenyl)-2-propyl)-2-propynylamine 
• 124401-48-5 1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrole-3-carboxaldehyde 
• 124401-46-3 1,2-diisopropyl-3-(hydroxymethyl)-4-(4-fluorophenyl)-1H-pyrrole 
• 122223-45-4 1-phenyl-2,5-dimethyl-4-(4-fluorophenyl)-1H-pyrrole-3-carboxaldehyde 

Relevant articles and documents

Substrate promiscuity of ortho-naphthoquinone catalyst: Catalytic aerobic amine oxidation protocols to deaminative cross-coupling and n-nitrosation

ortho-Naphthoquinone-based organocatalysts have been identified as versatile aerobic oxidation catalysts. Primary amines were readily cross-coupled with primary nitroalkanes via deaminative pathway to give nitroalkene derivatives in good to excellent yields. Secondary and tertiary amines were inert to ortho-naphthoquinone catalysts; however, secondary nitroalkanes were readily converted by ortho-naphthoquinone catalysts to the corresponding nitrite species that in situ oxidized the amines to the corresponding N-nitroso compounds. Without using harsh oxidants in a stoichiometric amount, the present catalytic aerobic oxidation protocol utilizes the substrate promiscuity feature to provide a facile access to amine oxidation products under mild reaction conditions.

Iron-catalyzed tandem one-pot addition and cyclization of the blaise reaction intermediate and nitroolefins: Synthesis of substituted NH-pyrroles from nitriles

The iron-catalyzed addition and cyclization of the Blaise reaction intermediate and nitroolefins to synthesize highly functionalized NH-pyrroles in a tandem one-pot manner from nitriles has been developed. This reaction shows good functional group tolerance and affords a broad spectrum of substituted NH-pyrroles in good yields. Copyright

Enzymatic enantiomeric resolution of phenylethylamines structurally related to amphetamine

Both enantiomers of several phenylethylamines, structurally related to amphetamine, have been prepared in good yields and excellent enantiomeric purity by enzymatic kinetic resolution using CAL-B and ethyl methoxyacetate as the acyl donor. In the case of the 4-hydroxyderivative of amphetamine (compound 4i), the S enantiomer racemized possibly in a dynamic kinetic resolution (DKR) under the enzymatic conditions used. The Royal Society of Chemistry 2011.