776298-34-1Relevant articles and documents
Efficient synthesis of isoplagiochin D, a macrocyclic bis(bibenzyls), by utilizing an intramolecular Suzuki-Miyaura reaction
Esumi, Tomoyuki,Wada, Mitsumasa,Mizushima, Eri,Sato, Norimasa,Kodama, Mitsuaki,Asakawa, Yoshinori,Fukuyama, Yoshiyasu
, p. 6941 - 6945 (2007/10/03)
Isoplagiochin D, a highly strained macrocyclic bis(bibenzyls) isolated from the liverwort Pladiochila fruticosa, was synthesized in 10.6% overall yield for the 11 steps by using Horner-Wadsworth-Emmons and Suzuki-Miyaura protocols. Isoplagiochin D, a highly strained macrocyclic bis(bibenzyls) with two biaryl units isolated from the liverwort Pladiochila fruticosa, was prepared in 10.6% overall yield for the 11 steps by an efficient synthetic approach involving the construction of two bibenzyl and one biaryl units using Horner-Wadsworth-Emmons and Suzuki-Miyaura protocols.