77744-18-4

Basic information

• Product Name: Acetic acid 1-(4-bromo-phenyl)-1-pyridin-3-yl-allyl ester
• Synonyms: Acetic acid 1-(4-bromo-phenyl)-1-pyridin-3-yl-allyl ester
• CAS NO: 77744-18-4
• Molecular Weight: 332.197
• Mol File: 77744-18-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid 1-(4-bromo-phenyl)-1-pyridin-3-yl-allyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid 1-(4-bromo-phenyl)-1-pyridin-3-yl-allyl ester(77744-18-4)
• EPA Substance Registry System: Acetic acid 1-(4-bromo-phenyl)-1-pyridin-3-yl-allyl ester(77744-18-4)

Safety Data

• Hazardous Substances Data: 77744-18-4(Hazardous Substances Data)

Upstream product

• 14548-45-9 (4-bromophenyl)-pyridin-3-yl-methanone 
• 10400-19-8 3-pyridinecarbonyl chloride 
• 108-24-7 acetic anhydride 
• 70263-43-3 1-(4-Bromophenyl)-1-(3-pyridyl)-2-propen-1-ol 

Downstream Products

• 56775-89-4 (E)-3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridyl)allylamine 
• 56775-88-3 Zimelidine 

Relevant articles and documents

Synthesis of 3-Aryl-3-pyridylallylamines Related to Zimelidine via Palladium-Catalyzed Amination

Reaction of aryl pyridyl ketones 1 with vinylmagnesium bromide followed by acetylation of the products 2 with acetic anhydride/Et3N and with 4-(dimethylamino)pyridine (DMAP) as a catalyst gave acetates 3 in high yields.Treatment of acetates 3 with dimethylamine in the presence of a palladium catalyst produced a mixture of E and Z isomers of 3-aryl-3-pyridylallylamines 4.